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U-Shaped Link for Fish Consumption, Mortality

Women only have increased mortality risk at the highest level of fish consumption

TUESDAY, Sept. 13, 2016 (HealthDay News) — There is a U-shaped correlation between fish consumption and all-cause mortality, according to a study published online Sept. 7 in the Journal of Internal Medicine.

Andrea Bellavia, Ph.D., from the Karolinska Institutet in Stockholm, and colleagues examined the dose-response association between fish consumption and all-cause mortality in a population-based cohort of Swedish men and women. Data were included for 72,522 participants aged 45 to 83 years (33,973 women from the Swedish Mammography Cohort and 38,549 men from the Cohort of Swedish Men). Data on fish consumption were obtained from a self-administered questionnaire.

The researchers found that during a 17-year follow-up there were 16,730 deaths. The dose-response association was U-shaped for fish consumption and all-cause mortality. Lower levels of consumption correlated with progressively higher mortality risk: up to 25 percent for women (hazard ratio, 1.25) and 19 percent for men (hazard ratio, 1.19) for no reported consumption compared with median fish consumption. For women only, increasingly higher levels of fish consumption correlated with higher mortality risk, with a hazard ratio of 1.39 for women reporting the highest level of fish consumption.

“These results indicate a U-shaped association between fish consumption and all-cause mortality, particularly amongst women,” the authors write.

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