Association between psoriasis and metabolic syndrome differs by sex
WEDNESDAY, Dec. 11, 2019 (HealthDay News) — Rates of type 2 diabetes may be higher among patients with psoriasis, according to a study published online Dec. 3 in the Journal of the European Academy of Dermatology and Venereology.
Wiebke Sondermann, Dr. Med., from University Duisburg-Essen in Germany, and colleagues analyzed data from 3,723 participants in the Heinz Nixdorf Recall study (ages 45 to 75 years; 54.1 percent women), who were free from coronary heart disease.
The researchers found that the prevalence of psoriasis was 3.8 percent, with no differences between men and women. Metabolic and cardiovascular risk factors were more common in women with psoriasis versus women without psoriasis. However, in men, this pattern was partly reversed. There were distinctly elevated prevalence rates (PRs) for type 2 diabetes for both women and men with psoriasis (fully adjusted PR, 2.43 [95 percent confidence interval (CI), 1.17 to 5.07] and 2.09 [95 percent CI, 1.16 to 3.76], respectively). For metabolic syndrome, the results were inconsistent, with a positive association between psoriasis and metabolic syndrome in women (PR, 1.84; 95 percent CI, 1.14 to 2.98) but a negative association in men (PR, 0.69; 95 percent CI, 0.42 to 1.12).
“Our results emphasize the urgent need for sex-specific research, studying the effects of psoriasis on metabolic disorders as well as effective sex tailored prevention measures,” the authors write.
Copyright © 2019 HealthDay. All rights reserved.
