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Roux-en-Y gastric bypass surgery attenuates markers of oxidative stress in subcutaneous adipose tissue

RYGB Cuts Markers of Oxidative Stress in Subcutaneous Tissue

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Fifty percent decrease in oxidative stress; no change in inflammatory markers in subcutaneous tissue
Beloranib seems efficacious and safe for weight loss in obese patients

Beloranib Safe, Efficacious for Weight Loss in Obesity

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Tolerable at doses of 0.6 and 1.2 mg; more adverse events with dose of 2.4 mg
'Thrifty' metabolism might sabotage weight loss efforts for some

Metabolic Response to Weight Loss Varies Greatly

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'Thrifty' metabolism possibly contributing to less weight lost
Calorie restriction and exercise-induced weight loss have additive benefits on glucoregulation

Additive Effect for Calorie Limit, Exercise on Glucoregulation

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Insulin sensitivity index values increased more in calorie restriction and exercise weight loss group
Reductions in liver fat or visceral adipose tissue do not differ significantly with the dose or intensity of aerobic exercise

Exercise Dose, Intensity Don’t Impact Reduction in Liver Fat

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In randomized trial, no difference in efficacy of liver fat reduction by aerobic exercise dose, intensity
Only two out of 32 major commercial weight-loss programs marketed nationwide -- Weight Watchers and Jenny Craig -- can boast scientific evidence showing their clients maintain weight loss for at least a year

Two Commercial Weight Loss Plans Come Out on Top

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Weight Watchers, Jenny Craig beat other commercial diet plans in new research
Motivational interviewing can help patients lose weight in a primary care setting

Motivational Interviewing Aids Weight Loss in Primary Care

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Review shows benefit for patients, with significant weight loss reported in 37.5 percent of studies
Lifestyle-based weight loss intervention trials in type 2 diabetes achieve modest reductions in weight and glycated hemoglobin levels

Lifestyle Interventions for Diabetes Yield Modest Results

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Findings based on pooled data regarding weight loss, HbA1c from 10 studies
Bariatric surgery cuts the risk of an emergency department visit or hospitalization for asthma exacerbation in obese patients by half

Bariatric Surgery May Help Reduce Asthma Exacerbations

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Obese asthma patients had half as many ER visits, hospitalizations after surgery
For obese patients with atrial fibrillation

ACC: Sustained Weight Loss Cuts A-Fib Burden

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Weight loss of >10 percent linked to six-fold increase in odds of arrhythmia-free survival