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For antipsychotic-treated obese patients with schizophrenia

Exenatide Does Not Promote Weight Loss in Schizophrenia

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No significant difference in weight loss for obese patients treated with exenatide, placebo
Patients with the FTO gene respond to weight-loss strategies as well as those without the gene

FTO Gene Does Not Inhibit Weight Loss Success

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Lifestyle, environment likely play bigger roles when losing weight, researchers say
Metformin may be effective in decreasing weight gain associated with atypical antipsychotic use in autism spectrum disorder

Metformin May Help Treatment-Associated Weight Gain in ASD

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Weight gain often a side effect of antipsychotic drugs used to treat irritability and agitation
For patients with type 1 diabetes

Addition of Dapagliflozin Improves Glycemia in T1DM

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Improvements in glycated hemoglobin, weight loss with addition of dapagliflozin to insulin, liraglutide
Overweight and obese women who lose weight via calorie restriction

Diet-Induced Weight Loss May Help Prevent CA in Obese Women

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Corresponding drop seen in circulating VEGF, PEDF, and PAI-1
Staying adequately hydrated may be associated with a lower risk of obesity

Inadequate Hydration Linked to Higher Odds of Obesity

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Well-hydrated adults tend to weigh less, researchers find
The addition of Roux-en-Y gastric bypass to lifestyle-medical management is associated with improved achievement of treatment goals in type 2 diabetes

Gastric Bypass Helps Achieve Diabetes Treatment Goals

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Lower mean HbA1c, more diabetes remission, more weight loss versus lifestyle-medical management
Gastric bypass surgery is associated with reduced symptoms and neurohormonal responses to hypoglycemia

Gastric Bypass Cuts Hormonal Responses to Hypoglycemia

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Reductions in glucagon, cortisol, catecholamine, and sympathetic nerve responses to hypoglycemia
Bariatric surgery is associated with improvements in adipose tissue function

Bariatric Surgery Improves Adipose Tissue Function

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Surgery alters distribution of fat mass from visceral to subcutaneous compartment
For patients with type 2 diabetes

Even Short-Term T2DM Remission Reduces Risk of Microvascular Dz

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Length of time spent in remission inversely related to risk of microvascular disease