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There is discordance in communication priorities for patients with ulcerative colitis and their gastroenterology physicians

Patient, Doctor Communication Priorities Differ in Ulcerative Colitis

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Second study highlights importance of recognizing the emotional impact of ulcerative colitis
A new clinical guideline from the American Gastroenterological Association published Dec. 18 in Gastroenterology focuses on the medical management of patients with mild-to-moderate ulcerative colitis.

Guideline Issued for Treatment of Mild/Moderate Ulcerative Colitis

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Standard-dose mesalamine or diazo-bonded 5-ASA recommended versus low-dose mesalamine
Psoriasis appears to be significantly associated with inflammatory bowel disease

Psoriasis Linked to Increased Risk for Inflammatory Bowel Disease

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Significant associations observed between psoriasis and risk for Crohn's disease, ulcerative colitis
Loss to follow-up is common with inflammatory bowel disease

Loss to Follow-Up Common With IBD, But Many Have Flare-Ups

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Predictors of follow-up loss are long travel time and low C-reactive protein levels at diagnosis
U.S. Food and Drug Administration approval of Xeljanz (tofacitinib) has been expanded to include adults with active moderate-to-severe ulcerative colitis

FDA Approves New Treatment for Ulcerative Colitis

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First oral medication approved for chronic use in moderate-to-severe active ulcerative colitis
For patients with acute severe ulcerative colitis

Predictors of Infliximab Response in Ulcerative Colitis Identified

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Baseline Mayo Endoscopic Score, CRP/albumin ratio predict treatment response and risk for colectomy
Clinical features

Clinical Feature Model Predicts Colitis Outcomes

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Clinical features can predict both colectomy and steroid dependence
Most patients with ulcerative colitis do not achieve the 'Treat to Target' end point of composite clinical and endoscopic remission

Most Ulcerative Colitis Patients Do Not Achieve Target Remission

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Thirty-five percent of patients in real-world care met target of clinical and endoscopic remission
Patients with moderate-to-severe ulcerative colitis who haven't done well on other treatments may have success with tofacitinib (Xeljanz)

Tofacitinib Found to Relieve Symptoms of Ulcerative Colitis

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But treatment isn't yet approved by FDA to treat inflammatory bowel condition
For patients with ulcerative colitis in clinical

Relapse Rate 18.6 Percent for Ulcerative Colitis

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Independent predictors of relapse were NSAID use and vitamin A intake for patients in remission