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An automated molecular assay can detect Mycobacterium tuberculosis with resistance to drugs directly from sputum specimens

Assay Can ID M. tuberculosis Resistance Mutations

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Assay detects mutations associated with resistance to isoniazid, fluoroquinolones, aminoglycosides

Change in Conversion Definition May Improve TB Detection

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Increase from IFNγ <0.2 to >0.7 IU/mL would improve identification of those at risk of tuberculosis
Isoniazid monotherapy

Meta-Analysis Compares Efficacy of Therapies for Preventing TB

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Isoniazid, rifampicin monotherapy, combination therapies can prevent active TB in latent TB infection
Multidrug-resistant and extensively drug-resistant tuberculosis are expected to increase through 2040

Multidrug-Resistant TB Set to Increase Through 2040

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Increase in percentage of MDR tuberculosis, XDR tuberculosis in India, Philippines, Russia, S. Africa
Deep learning with deep convolutional neural networks can result in accurate detection of tuberculosis on chest radiographs

Deep Convolutional Neural Networks Accurately Detect TB

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Ensemble of AlexNet and GoogLeNet was best-performing classifier, with AUC of 0.99
For patients with rheumatoid arthritis

Infection Risk Lower for Etanercept Vs Monoclonal Ab Rx

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Findings from meta-analysis of patients with rheumatoid arthritis
Migrants from countries with a high incidence of tuberculosis who undergo screening before entry to low-incidence countries pose a negligible risk of onward transmission but are at increased risk of the infection

Migrants Screened for Active TB Pose Negligible Transmission Risk

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Screening, monitoring, treatment important in continuing downward trend of tuberculosis incidence
According to a final recommendation statement from the U.S. Preventive Services Task Force published in the Sept. 6 issue of the Journal of the American Medical Association

USPSTF Recommends Latent Tuberculosis Infection Screening

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Screening for LTBI in persons at increased risk of infection provides moderate net benefit
From 2000 to 2011 there was a slight decline in the prevalence of latent tuberculosis infection in the United States

Slight Decline in U.S. Prevalence of Latent TB From 2000 to 2011

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Higher risk groups include foreign born, close contact with TB case, certain racial/ethnic groups
Two decades of progress toward eliminating tuberculosis in the United States has stalled

CDC: Tuberculosis Decline in the United States Has Hit a Plateau

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Agency reaffirms its commitment to eliminating the lung infection