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In a new clinical practice guideline

Recommendations Developed for Multidrug-Resistant Tuberculosis

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Use of at least five drugs recommended for intensive-phase treatment, four drugs for continuation phase
Childhood vaccination with the bacille Calmette-Guérin vaccine is associated with a reduced risk for lung cancer

Common TB Vaccine Associated With Lower Lung Cancer Rates

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In 60-year follow-up, significantly lower lung cancer rates seen for those with childhood BCG vaccination
Initiation of isoniazid preventive therapy during pregnancy is associated with increased risks versus initiation during the postpartum period

Isoniazid Tx to Prevent TB Ups Risks During HIV+ Pregnancy

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Deferring treatment until after delivery appears to be safer option
According to the U.S. Centers for Disease Control and Prevention

CDC Says People Can Contract Tuberculosis From Deer

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Anyone working closely with animals that might carry the infection should be screened for tuberculosis
An estimated 12.6 million persons in the United States could benefit from treatment to prevent active tuberculosis

12.6 Million in U.S. Could Benefit From Tx to Prevent Active TB

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Revised NHANES-based estimate for prevalence of latent TB infection excludes those who report prior tx
Overall tuberculosis rates are low among children and adolescents and are declining steadily

Tuberculosis Rates for U.S. Children Are Low and Declining

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Disparities persist by race, ethnicity, geography; incidence higher for those living in U.S.-affiliated islands
Guidelines have been updated for screening and treatment for tuberculosis infection among health care personnel

Recs Updated for TB Screening, Treatment in Health Care Workers

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Guidelines include preplacement TB risk assessment, postexposure symptom evaluation and testing
In 2017

CDC: TB Incidence Declined Slightly in United States in 2017

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Number of cases, disease incidence decreased globally, but more progress needed to meet targets
For HIV-infected patients

One-Month Regimen Noninferior for Preventing HIV-Related TB

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One-month rifapentine, isoniazid noninferior to nine months of isoniazid alone
A short regimen is noninferior to a long regimen for patients with rifampin-resistant tuberculosis that is susceptible to fluoroquinolones and aminoglycosides

Short Regimen Noninferior for Rifampin-Resistant Tuberculosis

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Short regimen of nine to 11 months noninferior to 20-month regimen following WHO guidelines