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Greater health system use and higher costs are seen with nine months of isoniazid compared with four months of rifampin in both adults and children treated for latent tuberculosis infection

Four Months of Rifampin Costs Less Than Nine Months Isoniazid

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Health system use and costs higher for nine months of isoniazid in adults and children in all settings
From 2017 to 2018

CDC: Modest Decreases Seen in TB Cases, TB-Related Deaths

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From 2017 to 2018, 2 and 5 percent declines seen in incident TB and TB-related deaths, respectively
The incidence of developing tuberculosis is high among exposed infants and young children

Incidence of Tuberculosis High in Children Exposed to the Disease

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Preventive therapy effective in most TB-infected children if given before development of active disease
For treatment of latent tuberculosis infection

Short-Course Rifamycin-Based Regimens Preferred for Latent TB

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Shorter regimens favored over longer course of isoniazid monotherapy for latent TB infection
In a new clinical practice guideline

Recommendations Developed for Multidrug-Resistant Tuberculosis

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Use of at least five drugs recommended for intensive-phase treatment, four drugs for continuation phase
Childhood vaccination with the bacille Calmette-Guérin vaccine is associated with a reduced risk for lung cancer

Common TB Vaccine Associated With Lower Lung Cancer Rates

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In 60-year follow-up, significantly lower lung cancer rates seen for those with childhood BCG vaccination
Initiation of isoniazid preventive therapy during pregnancy is associated with increased risks versus initiation during the postpartum period

Isoniazid Tx to Prevent TB Ups Risks During HIV+ Pregnancy

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Deferring treatment until after delivery appears to be safer option
According to the U.S. Centers for Disease Control and Prevention

CDC Says People Can Contract Tuberculosis From Deer

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Anyone working closely with animals that might carry the infection should be screened for tuberculosis
An estimated 12.6 million persons in the United States could benefit from treatment to prevent active tuberculosis

12.6 Million in U.S. Could Benefit From Tx to Prevent Active TB

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Revised NHANES-based estimate for prevalence of latent TB infection excludes those who report prior tx
Overall tuberculosis rates are low among children and adolescents and are declining steadily

Tuberculosis Rates for U.S. Children Are Low and Declining

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Disparities persist by race, ethnicity, geography; incidence higher for those living in U.S.-affiliated islands