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Ocular syphilis has been identified in jurisdictions in the United States

Ocular Syphilis Cases May Be Increasing in United States

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Among total syphilis surveillance cases in eight jurisdictions, 0.65 percent indicated ocular symptoms
Skin biopsies from patients co-infected with HIV and syphilis have moderate to extensive lymphoplasmacytic infiltrate

Lymphoplasmacytic Infiltrate Seen in Syphilis, HIV Co-Infection

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Skin biopsies show moderate to extensive infiltrate; quantity of treponemes linked to CD4 count
The U.S. Preventive Services Task Force recommends screening for syphilis infection in non-pregnant persons who are at increased risk of infection. These findings form the basis of a recommendation statement published in the June 7 issue of the Journal of the American Medical Association.

USPSTF Recommends Screening for Syphilis Infection

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Grade A recommendation for screening in non-pregnant persons at increased risk of infection
A case of acquired syphilis leading to involvement of the bone marrow and liver is described in a report published online March 22 in the Annals of Internal Medicine.

Report of Bone Marrow/Liver Pathology Caused by Syphilis

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Case study describes 65-year-old patient with late-latent syphilis with normocytic anemia
All adults and teens at increased risk for syphilis should be screened for the sexually transmitted disease

USPSTF: Screen All Teens, Adults at Risk for Syphilis

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Proposed recommendation dovetails with surge in U.S. cases of the sexually transmitted disease
Congenital syphilis cases increased 38 percent between 2012 and 2014

CDC: Sharp Increase in U.S. Babies Born With Syphilis

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Of infected babies born in 2014, 15 percent of mothers were never tested for syphilis
Universal third-trimester syphilis rescreening is not cost-effective given the national average seroconversion rate

Universal 3rd-Trimester Syphilis Rescreening Not Cost-Effective

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19-fold higher seroconversion incidence for universal rescreening to be cost-effective
Health care providers on the West Coast need to look out for syphilis that can cause blindness

Health Officials Warn of Blinding Cases of Syphilis on West Coast

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Doctors and eye-care providers should be alert for symptoms of ocular syphilis
A smartphone accessory that can detect HIV and syphilis has been developed by Columbia University researchers. The findings were published in the Feb. 4 issue of Science Translational Medicine.

Smartphone Accessory Could Help Detect HIV, Syphilis

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Low-cost accessory replicates laboratory-based blood test, researchers report