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Adding corticosteroids to initial intravenous immunoglobulin seems beneficial for preventing coronary artery abnormalities in high-risk patients with Kawasaki disease

Combination Therapy May Benefit Some With Kawasaki Disease

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Adding corticosteroids to initial IV immunoglobulin may reduce risk for coronary artery abnormalities
Prescriptions for oral steroid bursts are associated with a 1.8- to 2.4-fold increased risk for severe adverse events within the first month after initiation of drug therapy

Oral Corticosteroid Bursts Carry Risk for Severe Adverse Events

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Highest rates of adverse events seen within first month after initiating short course of oral steroids
For patients with rheumatic disease with COVID-19

COVID-19 Hospitalization Up With Prednisone in Rheumatic Disease

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No correlation seen for DMARD alone or in combination with biologics, Janus Kinase inhibitors, NSAIDs
For young patients with Crohn disease

Perianal Fistulizing Complications Preventable in Crohn Disease

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Steroid-sparing therapy may reduce risk for PFCs in young patients with Crohn disease
The cheap and widely available steroid dexamethasone reduced the risk for death among seriously ill COVID-19 patients by up to a third

Steroid May Reduce COVID-19 Death Risk by Up to One-Third

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Dexamethasone appears promising for patients with severe illness
For patients with inflammatory bowel disease and COVID-19

Corticosteroids for IBD May Up Risk for Severe COVID-19

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TNF antagonists not associated with severe COVID-19 in patients with inflammatory bowel disease
For adults with any of six chronic inflammatory diseases

Cumulative Dose of Oral Steroids Associated With HTN Incidence

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Incidence of hypertension higher for adults on oral steroids for any of six chronic inflammatory diseases
For adults with exacerbation of chronic obstructive pulmonary disease

Antibiotics, Corticosteroids Beneficial in COPD Exacerbations

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Independent of exacerbation severity, antibiotics tied to increased resolution, less treatment failure
Potent prescription-strength topical corticosteroids without a prescription are readily available in many U.S. cities

Potent, Unregulated Steroid Creams Readily Available in U.S.

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Potentially harmful, illegal topical steroids are being sold over the counter in foreign import stores
A quality improvement program can lower steroid use among patients with inflammatory bowel disease

Quality Improvement Program Lowers Prolonged Steroid Use With IBD

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Excess steroid use seen in 14 percent of patients