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ACR: Corticosteroid Injections Do Not Speed Progression of Knee OA

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Rates of radiographic progression similar for corticosteroid injections, hyaluronic acid injections in multivariable analysis

For patients with asthma

Corticosteroid Exposure Affects Bone Health in Asthma Patients

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Oral, inhaled corticosteroid use linked to increased risk for osteoporosis, fragility fractures
Children with current glucocorticoid exposure have increased risks for diabetes mellitus

Oral Steroids May Raise Risks for Diabetes, HTN, VTE in Children

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But absolute risks for these complications still low among children receiving glucocorticoids
For patients with rheumatoid arthritis  receiving disease-modifying antirheumatic drug therapy

Glucocorticoids Linked to Hospitalized Infection Risk in RA

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Risk for hospitalized infections up for patients with RA receiving DMARDs with continued glucocorticoid use
Steroids can improve survival in patients with COVID-19

Four Studies Indicate Benefits of Steroids for COVID-19

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Three randomized trials and a meta-analysis show benefits for critically ill patients, severe COVID-19
Adding corticosteroids to initial intravenous immunoglobulin seems beneficial for preventing coronary artery abnormalities in high-risk patients with Kawasaki disease

Combination Therapy May Benefit Some With Kawasaki Disease

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Adding corticosteroids to initial IV immunoglobulin may reduce risk for coronary artery abnormalities
Prescriptions for oral steroid bursts are associated with a 1.8- to 2.4-fold increased risk for severe adverse events within the first month after initiation of drug therapy

Oral Corticosteroid Bursts Carry Risk for Severe Adverse Events

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Highest rates of adverse events seen within first month after initiating short course of oral steroids
For patients with rheumatic disease with COVID-19

COVID-19 Hospitalization Up With Prednisone in Rheumatic Disease

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No correlation seen for DMARD alone or in combination with biologics, Janus Kinase inhibitors, NSAIDs
For young patients with Crohn disease

Perianal Fistulizing Complications Preventable in Crohn Disease

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Steroid-sparing therapy may reduce risk for PFCs in young patients with Crohn disease
The cheap and widely available steroid dexamethasone reduced the risk for death among seriously ill COVID-19 patients by up to a third

Steroid May Reduce COVID-19 Death Risk by Up to One-Third

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Dexamethasone appears promising for patients with severe illness