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Weight Gain, but No Increase in BP, Seen With Low-Dose Glucocorticoids in RA

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Glucocorticoids led to 1.1 kg more weight gain than control treatment over two years using data from five pooled RCTs

Studies Explore Risks for Exposure to Antenatal Corticosteroids

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Increased risk seen for serious infection during first 12 months of life and increased short-, long-term health outcomes

Dexamethasone Best for Persistent, Recurrent Uveitic Macular Edema

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Significantly greater reduction in macular edema seen with dexamethasone versus methotrexate, ranibizumab; BCVA significantly improved with dexamethasone during follow-up

Dexamethasone Compared to Burr-Hole Drainage for Chronic Subdural Hematoma

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Dexamethasone treatment was not noninferior with respect to functional outcomes and was associated with more complications

Hydrocortisone Does Not Reduce 90-Day Mortality in Septic Shock

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Small reduction in mortality seen with use of hydrocortisone with fludrocortisone

Prednisone Does Not Improve In Vitro Fertilization Outcomes

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Researchers observed increased risk for preterm delivery and biochemical pregnancy loss with prednisone

Dexamethasone Still Beneficial for Some Inpatients With COVID-19

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Odds of mortality or discharge to hospice reduced for those receiving supplemental oxygen or mechanical ventilation and/or ECMO

Cancer Risk Found to Be Higher in Asthma Patients

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However, inhaled steroids may offer protective effect

Hydrocortisone Plus Fludrocortisone Superior for Septic Shock

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Compared with hydrocortisone alone, combo significantly cuts risk for in-hospital death or hospice discharge

Pulsed Radiofrequency + Steroids Best for Sciatica From Herniated Disc

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Outcomes better with pulsed radiofrequency + transforaminal epidural steroid injection than injection alone in terms of leg pain severity, disability over one year after treatment