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Flovent Discontinuation in 2024 Raises Concerns for Doctors, Patients

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Flovent is being discontinued in the new year; insurance coverage of alternatives is uncertain

Osteoporosis Risk Increased With Long-Term Topical Corticosteroid Exposure

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Dose-response relationships identified between long-term exposure to TCSs and osteoporosis and major osteoporotic fracture

Dexamethasone No Benefit in HIV-Positive With Tuberculous Meningitis

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No survival benefit or benefit in any secondary end point seen for adjunctive dexamethasone versus placebo

Lavage + Steroid No Benefit in Calcific Rotator Cuff Tendinopathy

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No benefit seen for ultrasound-guided lavage with a corticosteroid injection for calcific rotator cuff tendinopathy of shoulder

Weight Gain, but No Increase in BP, Seen With Low-Dose Glucocorticoids in RA

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Glucocorticoids led to 1.1 kg more weight gain than control treatment over two years using data from five pooled RCTs

Studies Explore Risks for Exposure to Antenatal Corticosteroids

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Increased risk seen for serious infection during first 12 months of life and increased short-, long-term health outcomes

Dexamethasone Best for Persistent, Recurrent Uveitic Macular Edema

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Significantly greater reduction in macular edema seen with dexamethasone versus methotrexate, ranibizumab; BCVA significantly improved with dexamethasone during follow-up

Dexamethasone Compared to Burr-Hole Drainage for Chronic Subdural Hematoma

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Dexamethasone treatment was not noninferior with respect to functional outcomes and was associated with more complications

Hydrocortisone Does Not Reduce 90-Day Mortality in Septic Shock

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Small reduction in mortality seen with use of hydrocortisone with fludrocortisone

Prednisone Does Not Improve In Vitro Fertilization Outcomes

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Researchers observed increased risk for preterm delivery and biochemical pregnancy loss with prednisone