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For healthy subjects

Prednisolone Therapy Induces Procoagulant State

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Ten days of treatment linked to increase in peak thrombin, velocity index, PAI-1, and vWF
Inhibition of mammalian target of rapamycin by rapamycin restores corticosteroid sensitivity in patients with chronic obstructive pulmonary disease

Inhibition of mTOR Restores Corticosteroid Sensitivity in COPD

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mTOR inhibition by rapamycin restores corticosteroid sensitivity via c-Jun expression inhibition
Two new studies offer insight into what might -- or might not -- help treat knee osteoarthritis. Both studies were presented this week at the annual meeting of the American College of Rheumatology

ACR: Steroids Little Help, Ozone Injections Promising for Knee OA

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Two studies test out old and new treatments for knee osteoarthritis
For patients with pemphigus vulgaris

Remission in Pemphigus Vulgaris With Strategic Steroid Tapering

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Strategy of 50 percent per year reduction in glucocorticoid dose deemed viable
Epidural corticosteroid injections for radicular low back pain or spinal stenosis may provide some relief for certain patients

Corticosteroid Injections of Little Benefit for Low Back Pain

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Any relief is likely temporary, review of 38 studies finds
For hospitalized adults with community-acquired pneumonia

Systemic Corticosteroid Therapy Can Improve Outcomes in CAP

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Mortality, need for mechanical ventilation, hospital stay down in community-acquired pneumonia
A subgroup of patients with dermatitis who discontinue topical corticosteroids after long-term treatment have clinical rebounding triad manifestations

Clinical Rebounding Triad After Corticosteroid Discontinuation

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Duration and frequency of topical corticosteroid use predicts rebounding triad
For kidney transplant recipients

Steroid Avoidance May Not Help Reduce Posttransplant Diabetes

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Limited effect among adult patients during five years following kidney transplantation
Asthma treatments

Asthma Rx Deemed Less Likely to Work in Patients Aged 30 and Up

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Having respiratory condition for longer time, lower lung function may be factors
Oral prednisone is no more effective than placebo for sciatica pain and provide only modest improvement in function

Prednisone for Sciatica No Better Than Placebo

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But steroid was tied to small improvements in ability to perform daily activities