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For children with acute otitis media with tympanostomy tubes

Ciprofloxacin Plus Fluocinolone More Effective for Peds AOMT

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More effective than ciprofloxacin or fluocinolone alone for acute otitis media w/tympanostomy tubes
Evidence that wet wrap therapy is more effective than topical steroids for the treatment of atopic dermatitis is mixed

Efficacy of Wet Wrap Therapy for Atopic Dermatitis Undetermined

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Wet wrap therapy may pose higher risk of local infections than topical steroids
Transient addition of topical corticosteroids to topical retinoids is not associated with meeting the primary end points of improvement in acne severity and mitigation of medication-induced irritation

Transient Topical Corticosteroids of Limited Use in Acne

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Doesn't meet primary end points of improved acne severity, mitigation of retinoid-induced irritation
Supplemental testosterone and related anabolic-androgenic steroids can cause heart attacks

FDA Warns of Testosterone, AAS Abuse and Dependence

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Many American men take them, but heart and psychological issues can occur, agency says
Daily intranasal corticosteroids (INCS) are not superior to on-demand INCS or to antihistamine on demand for the treatment of pollen-related allergies in children

Daily Intranasal Steroid Tx Not Better for Allergy Relief

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Findings based on number of symptom-free days for daily versus as-needed treatment
Even partial steroid treatment before birth can improve survival odds for extremely premature infants and reduce their risk of certain birth defects

Even Partial Antenatal Steroid Treatment Benefits Preemies

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Fewer deaths, complications for extremely premature infants
The use of hydrocortisone does not reduce the risk of septic shock within 14 days among adults with severe sepsis not in septic shock

Hydrocortisone Doesn’t Cut Risk of Septic Shock in Sepsis

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Among adults with severe sepsis not in septic shock, no reduction in septic shock with hydrocortisone
Use of anabolic androgenic steroids may lead to insulin resistance

Misuse of Anabolic Steroids Linked to Insulin Resistance

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Effect may be mediated by increased visceral adipose tissue as primary metabolically active fat tissue
For patients with Lyme disease-associated facial palsy

Corticosteroids Linked to Worse Outcome in Facial Palsy

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Worse facial function outcomes for patients with Lyme disease-associated facial palsy
Whole brain radiotherapy seems to offer limited clinical benefit for patients with non-small-cell lung cancer with metastases

Whole Brain Radiotherapy Offers Little Benefit in Brain Mets

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Randomized trial shows limited clinical benefit for patients with NSCLC and brain metastases