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Even partial steroid treatment before birth can improve survival odds for extremely premature infants and reduce their risk of certain birth defects

Even Partial Antenatal Steroid Treatment Benefits Preemies

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Fewer deaths, complications for extremely premature infants
The use of hydrocortisone does not reduce the risk of septic shock within 14 days among adults with severe sepsis not in septic shock

Hydrocortisone Doesn’t Cut Risk of Septic Shock in Sepsis

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Among adults with severe sepsis not in septic shock, no reduction in septic shock with hydrocortisone
Use of anabolic androgenic steroids may lead to insulin resistance

Misuse of Anabolic Steroids Linked to Insulin Resistance

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Effect may be mediated by increased visceral adipose tissue as primary metabolically active fat tissue
For patients with Lyme disease-associated facial palsy

Corticosteroids Linked to Worse Outcome in Facial Palsy

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Worse facial function outcomes for patients with Lyme disease-associated facial palsy
Whole brain radiotherapy seems to offer limited clinical benefit for patients with non-small-cell lung cancer with metastases

Whole Brain Radiotherapy Offers Little Benefit in Brain Mets

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Randomized trial shows limited clinical benefit for patients with NSCLC and brain metastases
For adult patients with chronic rhinosinusitis

Intranasal Steroids Underused in Chronic Rhinosinusitis

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Rate of intranasal steroid spray utilization 20.1 per 100 patients; geographic variation in rate
Postnatal corticosteroid use may increase premature infants' risk of retinopathy of prematurity

Postnatal Steroids Tied to Higher Ocular Risk for Premature Infants

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Risk of retinopathy of prematurity was 60 percent higher for infants treated with corticosteroids
Antenatal administration of corticosteroids is not associated with a reduction in the incidence of respiratory distress syndrome in preterm twins

Antenatal Steroids Don’t Cut Morbidity in Preterm Twins

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No reduction in incidence of respiratory distress syndrome or composite neonatal morbidity
High-dose methylprednisolone does not prevent platelet decline in women with preeclampsia and platelet counts below 150 × 109/L

High-Dose Steroid No Benefit to Platelets in Preeclampsia

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High-dose methylprednisolone no benefit for women with preeclampsia, platelet counts <150 × 109/L
Patients taking systemic glucocorticoids are at higher risk for community-acquired Staphylococcus aureus bacteremia

Risk of S. aureus Bacteremia Up in Patients on Glucocorticoids

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Community-acquired Staphylococcus aureus bacteremia risk rose along with the dosage