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Regular use of corticosteroid injections for degenerative knee disease is ineffective and may even result in cartilage loss

No Evidence Steroids Benefit Symptomatic Knee Osteoarthritis

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Noticeable cartilage loss detected in patients treated with injections over two years, researchers say
From 2011 to 2015 there was an increase in annual spending and out-of-pocket spending on topical steroids

Spending on Topical Steroids Up From 2011 to 2015

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During study time period, generic medication costs accounted for 97.8 percent of total spending
A single dose of oral dexamethasone only offers modest benefit in the treatment of acute sore throat

Dexamethasone Found to Be of Little Benefit in Acute Sore Throat

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Study seeking antibiotic alternatives found that only one-third of patients improved within 48 hours
Exposure to repeat doses of antenatal betamethasone is not associated with alterations in bone mass in mid-childhood compared with a single course of glucocorticoids

Antenatal Betamethasone Doesn’t Impact Pediatric Bone Mass

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No alterations in bone mass in mid-childhood with repeat doses of antenatal betamethasone
For extremely preterm infants

Hydrocortisone Tx Doesn’t Impair Neurodevelopment in Preemies

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No statistically significant difference in neurodevelopment at 2 with hydrocortisone, placebo
Use of corticosteroids is associated with increased odds of metabolic syndrome and elevated body mass index

ENDO: Corticosteroids Linked to Increased Risk of MetS

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CS users had higher odds of metabolic syndrome, increased body mass index compared with nonusers
Among infants born from 23 to 34 weeks of gestation

Extreme Preemies Benefit Most From Corticosteroids Before Birth

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Effect size of corticosteroid exposure on mortality greater at lowest gestations
Budesonide oral suspension is associated with improvement in symptomatic

Novel Oral Budesonide Prep Treats Eosinophilic Esophagitis

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Phase 2 study shows significant improvements in symptomatic, endoscopic, histologic parameters
For patients with chronic low back pain with active discopathy

Intradiscal Steroid Offers Short-Term Relief of Lower Back Pain

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Reduction in pain at one month, but not 12 months, for chronic low back pain with active discopathy
Inhaled corticosteroids do not appear to be associated with the risk of pneumonia in children with asthma

Inhaled Corticosteroids Not Linked to Pneumonia in Children

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No increased risk of pneumonia; no link for ICS with risk of pharyngitis, otitis media, sinusitis