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For patients with chronic obstructive pulmonary disease

Once-Daily Triple-Tx Improves Lung Function, HRQoL in COPD

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Significantly improved FEV1 and St. George's Respiratory Questionnaire scores
Oral methylprednisolone is associated with increased risk of serious adverse events among patients with immunoglobulin A nephropathy and proteinuria of greater than 1 g/day

Methylprednisolone Ups Adverse Events in IgA Nephropathy

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Recruitment discontinued because of serious adverse events after randomization of 262 patients
For patients undergoing elective unilateral total knee arthroplasty

Pre-Op Methylprednisolone Beneficial in Knee Arthroplasty

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Linked to reduced circulating markers of endothelial activation and damage
For older patients receiving prednisolone

Alendronate Cuts Hip Fx Risk in Seniors Taking Prednisolone

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No association for alendronate treatment with risk of mild upper GI symptoms, peptic ulcers
Benralizumab is associated with a significant reduction in glucocorticoid doses among adults with severe asthma

ATS: Benralizumab Reduces Glucocorticoid Doses in Asthma

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Significant 75 percent reduction in median final oral glucocorticoid doses from baseline
Patients with a short cervix who deliver prematurely have a significantly longer interval from antenatal corticosteroid administration

Study Questions Utility of Universal Cervical Length Screens

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Fewer patients with short cervix delivering prematurely received steroids within 7 days of birth
Regular use of corticosteroid injections for degenerative knee disease is ineffective and may even result in cartilage loss

No Evidence Steroids Benefit Symptomatic Knee Osteoarthritis

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Noticeable cartilage loss detected in patients treated with injections over two years, researchers say
From 2011 to 2015 there was an increase in annual spending and out-of-pocket spending on topical steroids

Spending on Topical Steroids Up From 2011 to 2015

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During study time period, generic medication costs accounted for 97.8 percent of total spending
A single dose of oral dexamethasone only offers modest benefit in the treatment of acute sore throat

Dexamethasone Found to Be of Little Benefit in Acute Sore Throat

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Study seeking antibiotic alternatives found that only one-third of patients improved within 48 hours
Exposure to repeat doses of antenatal betamethasone is not associated with alterations in bone mass in mid-childhood compared with a single course of glucocorticoids

Antenatal Betamethasone Doesn’t Impact Pediatric Bone Mass

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No alterations in bone mass in mid-childhood with repeat doses of antenatal betamethasone