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A clinical trial assessing the use of stem cells to treat heart failure patients has been paused by the U.S. National Heart

Cardiac Stem Cell Trial Halted Due to Concerns About Fake Data

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CONCERT-HF trial on hold while data and safety monitoring board conducts review
The U.S. Food and Drug Administration has launched legal action to stop two stem cell clinics from providing unapproved treatments that have caused serious

FDA Targets Clinics Offering Unapproved Stem Cell Therapies

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Clinics claim unapproved therapies can treat number of diseases and conditions, including ALS and cancer
Crowdfunding campaigns for unproven stem cell-based interventions tend to exaggerate the efficacy and underemphasize the risks

Crowdfunding Exaggerates Efficacy of Unproven Stem Cell Tx

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Crowdfunding campaigns for unproven stem cell-based interventions underemphasize risks
Despite low-level evidence

AAOS: Stem Cell Tx for Knee OA Costs About $5,000 Per Injection

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High cost, rapidly expanding use despite low-level evidence; mean marketed clinical efficacy of 82.2%
Induced pluripotent stem cell vaccines prevent tumor growth in syngeneic murine cancer models in a prophylactic setting

Induced Pluripotent Stem Cell Vaccine Promising for Cancer

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iPSC vaccine prevented tumor growth in syngeneic murine breast CA, mesothelioma, melanoma models
Stem cell transplant may be an effective treatment for systemic sclerosis

Stem Cell Transplant May Be Effective for Systemic Sclerosis

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Small study shows improvements in management of cutaneous, organ manifestations
Hematopoietic stem/progenitor cell-derived chimeric antigen receptor T-cells are capable of long-term engraftment in a model of HIV/AIDS

HSPC-Derived CAR T-Cells Capable of Lasting Engraftment

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Chimeric antigen receptor T-cells persisted more than 2 years without measurable toxicity in primate model
Infusion of autologous umbilical cord blood improves whole brain connectivity and motor function in young children with cerebral palsy

Cord Blood Improves Motor Function With Cerebral Palsy

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Improved brain connectivity, motor function seen in dose-dependent manner
Human embryonic stem cell-derived retinal pigment epithelial cells transplanted subretinally are safe for advanced dry-form age-related macular degeneration (AMD) as well as for atrophic AMD and Stargardt disease

AAO: Stem Cell Retinal Pigment Epithelial Cells Safe in Dry AMD

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And subretinal hESC-derived RPE suspension safe in age-related macular degeneration, Stargardt disease
After hematopoietic stem cell transplantation for acute leukemia

Leukemia Patients Who Survive Severe GVHD Often Fare Worse

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Those who develop severe acute graft-versus-host after stem cell transplant have higher mortality