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Allogeneic hematopoietic cell transplantation with an unrelated donor results in better transplantation outcomes than cord blood transplantation in acute myeloid leukemia patients with active disease

Allo-HCT With Unrelated Donor Tied to Better Outcomes in AML

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In active AML, outcomes superior for allo-HCT with unrelated donor than for cord blood transplantation
A tool has been developed that can improve standardization and transparency when describing cell therapies

Experts Develop Standardized Tool for Describing Cell Therapies

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Consensus reached on contents of DOSES tool for improving standardization and transparency
For older patients undergoing allogeneic hematopoietic cell transplantation

Population Mortality Affects Long-Term Follow-Up of AlloHCT

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Substantial part of total nonrelapse mortality for older patients due to population mortality
A consensus statement for the use of hematopoietic stem cell transplantation in the treatment of multiple myeloma has been developed by Mayo Clinic physicians; the recommendations were published in the March issue of Bone Marrow Transplantation.

Recommendations Issued for HSCT in Multiple Myeloma

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Autologous stem cell transplant remains essential component of MM therapy in eligible patients
For children with B-cell precursor acute lymphoblastic leukemia with late bone marrow relapse

Favorable Outcomes Seen in Long Term for ALLR3 Trial

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Findings for risk-stratified tx in B-cell precursor acute lymphoblastic leukemia, late bone marrow relapse
In only the second known case worldwide

Second Man HIV-Free After Stem Cell Transplant

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Donor had double copy of gene mutation that confers natural resistance to HIV
Autologous stem cell transplantation may be beneficial for some patients with nodal peripheral T-cell lymphoma in the first complete remission

Autologous Stem Cell Transplant May Aid Some With Nodal PTCL

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Prospective cohort study suggests benefit of ASCT for some with nodal peripheral T-cell lymphoma
For some children with hypodiploid acute lymphoblastic leukemia

Addition of BMT Not Indicated in Some With Peds Hypodiploid ALL

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Bone marrow transplant not beneficial if no minimal residual dz after remission induction tx
For patients with relapsing-remitting multiple sclerosis

Stem Cell Transplant Slows Progression of Multiple Sclerosis

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Findings from small randomized trial comparing nonmyeloablative HSCT with disease-modifying tx
After infections tied to unapproved stem cell treatments sent 12 people to the hospital this past year

FDA Warns Companies on Unsafe, Unapproved Stem Cell Treatments

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Patients contracting deadly infections at clinics offering the unapproved treatments