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Tag: Statins

Daily atorvastatin is safe for the primary prevention of cardiovascular events (CVE) in patients with rheumatoid arthritis

Statins Safe, Effective in Rheumatoid Arthritis Patients

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However, cardiovascular event rates are low, do not require a primary prevention strategy for all patients
More than half of patients initiating statin therapy have a suboptimal low-density lipoprotein cholesterol response within 24 months

Over Half of Patients Have Suboptimal Response to Statins

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Suboptimal responders have increased risk for incident cardiovascular disease
More than half of patients eligible for statin therapy but not being treated report never being offered a statin

Many Eligible Patients Report Not Being Offered Statins

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Fear of side effects, perceived side effects most common reasons for declining, discontinuing statins
Statins reduce the rate of vascular events regardless of patient age

Statins Cut Risk for Major Vascular Events in Older Patients

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Effects seen even among patients older than 75 years, though with less direct evidence of benefit
Individuals using statins may be at higher risk for hyperglycemia

Statins Tied to Insulin Resistance, Higher Serum Fasting Insulin

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Ever use of statins associated with 38 percent increased risk for incident type 2 diabetes
Few patients are optimally adherent to statins

ACC: Adherence to Statins Low Among Patients With ASCVD

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Adherence linked to significantly reduced risk for MACE, but only 6.4 percent had optimal compliance
For Taiwanese patients with type 2 diabetes and dyslipidemia

Statin Therapy Reduces Risk for Diabetic Retinopathy in T2DM

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Reduced risk, slowed progression of retinopathy for Taiwanese patients with type 2 diabetes, dyslipidemia
Adherent patients receiving high-intensity statin and/or ezetimibe therapy have the lowest cardiovascular risk

Adherence and Intensity of Lipid-Lowering Tx Influence CV Risk

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Lowest risk seen for adherent patients receiving high-intensity statin and/or ezetimibe regimen
Statins are associated with a low risk for side effects

AHA Scientific Statement: Low Risk of Side Effects for Statins

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Risk for statin-induced serious muscle injury <0.1 percent, newly diagnosed diabetes ~0.2 percent
The onset of musculoskeletal adverse events during statin monotherapy is significantly faster with use of atorvastatin and rosuvastatin versus simvastatin

Onset of Musculoskeletal Adverse Events Varies Between Statins

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Significantly faster onset with atorvastatin, rosuvastatin versus simvastatin during monotherapy