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Genetic Variants in HMGCR Linked to Increased Cataract Risk

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Heterozygous carriers of HMGCR predicted loss-of-function variants had higher risks for developing cataract, cataract surgery

USPSTF Updates Guidance on Statins for Primary Prevention of CVD

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Statin use recommended for people aged 40 to 75 years with CV risk factor(s) and higher 10-year risk for a CV event

More Intensive LDL-C Lowering May Cut Recurrent Stroke Risk

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More intensive LDL-C-lowering with statin-based therapies linked to reduced risk for recurrent stroke for patients with evidence of atherosclerosis

Meta-Analysis Shows Prevalence of Statin Intolerance Is Low

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Prevalence of SI was 9.1 percent overall; significant associations seen for age, female gender, Asian and Black race, obesity, diabetes mellitus

Statin Use May Be Safely Continued During Pregnancy

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Higher risk seen for low birth weight and preterm birth with statins, but no tie to congenital anomalies

Statin Use Not Linked to COVID-19 Mortality in Hospitalized Patients

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Statin use associated with increased relative risk for severe disease among hospitalized patients with COVID-19

Statins May Be Tied to Lower Risk for COVID-19 Death

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Statin treatment tied to moderately lower COVID-19 mortality in large population study accounting for preexisting health conditions and other factors

Fixed-Dose Combination Therapies Reduce Cardiovascular Risk

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Fixed-dose combo with BP-lowering meds, statin, and aspirin yields largest reduction in cardiovascular risk

Statin Use Improves Survival in Triple-Negative Breast Cancer

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Overall survival, breast cancer-specific survival improved among women with TNBC, but not those without TNBC

Prior Statin Use Linked to Reduced Risk for Death in COVID-19

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Risk for death significantly reduced with prior statin and/or antihypertensive use among those with history of CVD and/or hypertension