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Statins are efficacious and safe for reducing the risk of vascular events

Review of Evidence Confirms Efficacy of Statin Therapy

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Larger absolute benefits for prolonged therapy; benefits outweigh rare cases of adverse events
A disease-guided approach to statin eligibility can improve treatment specificity

Disease-Guided Approach Ups Specificity of Statin Treatment

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Improvement in specificity for coronary heart disease events with CAC-, cPB-guided reclassification
For patients with diabetes

Statin Use Tied to Reduced Risk of Parkinson’s in Diabetes

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Protective effects for all statins, except lovastatin; evidence of dose-dependent trend
Most Medicare fee-for-service beneficiaries with dyslipidemia who initiate statins undergo baseline alanine aminotransferase and aspartate aminotransferase testing

Baseline ALT, AST Frequently Assessed With Statin Initiation

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Baseline testing rates 89.3, 88.8 percent for alanine aminotransferase, aspartate aminotransferase
Statins may help lower mortality in patients with four common types of cancer

Statins Could Help Boost Survival Among Cancer Patients

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Study found an association -- but no proof -- of prolonged survival
Alanine aminotransferase levels within normal range are associated with cardiovascular event risk

ALT Levels Within Normal Range Linked to Cardiovascular Events

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Incident cardiovascular events were highest for those in the lowest tertile of baseline ALT
Statins could significantly reduce the risk of infection in stroke patients

Statins Could Reduce Risk of Infection in Stroke Patients

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Meds may have anti-inflammatory properties that help the body respond to infection
Very low target low-density lipoprotein cholesterol levels may not benefit all patients with preexisting heart disease

Moderately Low LDL May Be Enough to Ward Off CVD Risk

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Researchers find reduction to 70 mg/dL range not associated with additional benefit
Statins may spare patients with peripheral artery disease from the possibility of amputation and even death

Statins Might Help Prevent Amputation in PAD Patients

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Cholesterol-lowing drugs associated with reduced risk of amputation, mortality
Taking statins right before cardiac surgery

No Benefit Found for Perioperative Statin Therapy

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Statins don't prevent complications and may cause acute kidney injury, researchers report