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Only about 50 percent of adults with familial hypercholesterolemia are on statin therapy

Only Half of Adults With Familial Hypercholesterolemia on Statins

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And, only 30.3 percent of patients with definite or probable FH on statins take high-intensity statin
In women with type 2 diabetes

No Link Found for Metformin or Statins and Ovarian Cancer

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Findings based on a Finnish study involving a national cohort of women with type 2 diabetes
Compliance with guideline-directed medical therapy is low

Guideline-Directed Medical Tx Adherence Low Post CABG

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Compliance higher in PCI than CABG, but remains low in contemporary clinical trials
For patients who have experienced an atherosclerotic cardiovascular disease event

AHA: Statins Cut Risk of MACE in Patients With ASCVD Event

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Reduced frequency of MACE for patients receiving statins, especially high-intensity statins
For populations at high-risk for diabetes

Statins May Raise Odds of T2DM in Those at High Risk

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In any Diabetes Prevention Program treatment group, statin use tied to increased diabetes risk
Statin use is associated with a decreased risk of community-acquired Staphylococcus aureus bacteremia

Statins Tied to Lower Community-Acquired Staph Infection Risk

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Decrease in risk of Staphylococcus aureus bacteremia is seen especially with long-term statin use
Nonadherence to angiotensin-converting enzyme inhibitors/angiotensin II receptor blockers and/or statins following acute myocardial infarction is associated with higher mortality

Nonadherence to Statins + ACEIs/ARBs Risky Post MI

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Adherence to beta-blockers may not be as beneficial to patients after myocardial infarction
Statin use is associated with a significantly lower risk of mortality in older male physicians

Lower Mortality Risk Seen With Statin Use in Older Men

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Also tied to a non-significant lower risk of cardiovascular disease events
Statin use is associated with a reduced risk of all-cause and pulmonary-related mortality in patients with chronic obstructive pulmonary disease

Statins Tied to Reduced Mortality Risk in COPD

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Statin exposure associated with lower all-cause, pulmonary mortality
There is no significant difference in cognitive function for patients treated with evolocumab or placebo added to statin therapy

Evolocumab Doesn’t Affect Cognition When Added to Statins

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No significant between-group difference for patients receiving evolocumab or placebo added to statins