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Some cases of subacute cutaneous lupus erythematosus and systemic lupus erythematosus are drug-induced

Some Lupus Erythematosus Cases Tied to Drug Exposure

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Cases found for both cutaneous and systemic lupus, but some previous reports due to protopathic bias
Contemporary survivors of childhood acute lymphoblastic leukemia have reduced late morbidity and mortality

Late Morbidity, Mortality Down for Survivors of Childhood ALL

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Compared with 1970s, rate of subsequent malignant neoplasms lower with standard-risk 1990s-like therapy
The efficacy of hormonal contraceptives may be reduced with use of antibiotics

Antibiotics May Reduce Efficacy of Hormonal Contraceptives

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Unintended pregnancies seven times more commonly reported with antibiotics than control medicines
The permanent birth control device Essure is associated with higher rates of chronic lower abdominal or pelvic pain and abnormal uterine bleeding compared with tubal ligation

Higher Rates of Pain, Bleeding Found With Essure Birth Control Device

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In 2018, Essure maker Bayer pulled the device from the U.S. market due to concerns about side effects
Prescriptions for oral steroid bursts are associated with a 1.8- to 2.4-fold increased risk for severe adverse events within the first month after initiation of drug therapy

Oral Corticosteroid Bursts Carry Risk for Severe Adverse Events

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Highest rates of adverse events seen within first month after initiating short course of oral steroids
Inhibition of sclerostin with romosozumab may increase cardiovascular risk

Inhibition of Sclerostin May Increase Cardiovascular Risk

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SOST genetic variants linked to lower risk for fracture and osteoporosis but higher risk for MI, major CV AEs
There is a small increased risk for subdeltoid bursitis after influenza vaccination

Small Increase Seen in Risk for Subdeltoid Bursitis With Flu Shot

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Attributable risk was 7.78 additional cases of subdeltoid bursitis per million persons vaccinated
Patients with COVID-19 who receive hydroxychloroquine have a high risk for corrected QT prolongation

Hydroxychloroquine in COVID-19 Ups Risk for QTc Prolongation

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Concurrent treatment with azithromycin linked to greater changes in corrected QT interval
Anticholinergic burden is associated with adverse outcomes in a middle- to older-aged population

Anticholinergic Burden Tied to Adverse Effects in Middle Age

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Identification of at-risk populations varies by scale used, which could impact clinical practice
Asthma and allergy drug montelukast -- sold as a generic and under the brand name Singulair -- will get a "boxed warning" over potential ties to neuropsychiatric effects

FDA: Singulair to Get ‘Black Box’ Warning

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Drug has long carried warning of potentially dangerous neuropsychiatric side effects