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Administration of a tamoxifen-phospholipid complex is associated with improvement in tamoxifen-induced hepatotoxicity in rats

Tamoxifen-Phospholipid Complex May Alleviate TMX Toxicity

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Rat study demonstrates improvement in tamoxifen-induced hepatotoxicity with TMX-PLC
For women with breast cancer

Hypofractionated Breast Irradiation = Reduced Toxicity

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Two studies show benefits for hypofractionated vs conventionally fractionated whole-breast irradiation
For canagliflozin-treated patients with type 2 diabetes

Low Incidence of Diabetic Ketoacidosis With Canagliflozin

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Canagliflozin-treated patients with type 2 diabetes have low incidence of serious adverse DKA events
Adverse reactions to St. John's wort are similar to those reported for fluoxetine

Similar Adverse Effects Seen for St. John’s Wort, Fluoxetine

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Majority reported concern females, 26 to 50 years of age
About 10 percent of cases where a drug does serious harm are not reported to the U.S. Food and Drug Administration within the required 15-day period

Delays Noted in the Reporting of Serious Patient Harms to FDA

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Analysis found roughly 10 percent of cases were filed after 15-day deadline passed