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Statins are efficacious and safe for reducing the risk of vascular events

Review of Evidence Confirms Efficacy of Statin Therapy

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Larger absolute benefits for prolonged therapy; benefits outweigh rare cases of adverse events
Stronger warnings about the possible side effects of fluoroquinolones were issued Thursday by the U.S. Food and Drug Administration.

FDA Issues Stronger Warning on Side Effects of Fluoroquinolones

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Agency is recommending that health care providers not prescribe them for certain patients
The synthetic prostaglandin E1 analogue misoprostol has known severe side effects and should be considered in cases of postpartum hyperthermia

Misoprostol Should Be Considered in Postpartum Hyperthermia

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Report of 21-year-old with severe hyperthermia, rigors, tachycardia, transient encephalopathy
Anti-programmed cell death-1 therapy for metastatic melanoma is associated with the development of immune-related cutaneous events

Melanoma Therapy Tied to Cutaneous Adverse Events

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Anti-programmed cell death-1 therapy tied to lichenoid reactions, eczema, vitiligo
For children with infantile hemangiomas

Serious Propranolol ADRs Rare in Infantile Hemangioma

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Most commonly reported adverse drug reactions were respiratory disorders
Dysgraphia after sertraline intake has been documented in a case report published online Jan. 21 in the Journal of Clinical Pharmacy and Therapeutics.

Dysgraphia Described After Sertraline Intake

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Case report describes 60-year-old man with tremors and episodes of buccal dyskinesia, dysgraphia
Excessive hair growth can occur after local administration of interferon-β treatment for malignant melanoma

Excessive Hair Growth Documented After IFN-β Tx

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Patient received localized IFN-β treatment after resection of malignant melanoma on right thigh
For men with metastatic prostate cancer

More Adverse Effects for Medical Castration in Prostate Cancer

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Higher risks of several clinically relevant adverse effects compared with surgical castration
More frequent monitoring may be required when patients are taking both acenocoumarol and levofloxacin due to the possibility of an adverse interaction

Interaction Described Between Acenocoumarol, Levofloxacin

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Probable interaction described in five patients, all of whom had atrial fibrillation
Animal studies have uncovered a compound that might reduce the adverse effects of levodopa. The research was published in the Nov. 18 issue of Neuron.

New Compound May Help Reduce Side Effects From Levodopa

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Studies in mice, monkeys point to a compound that might lessen levodopa's debilitating effects