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Tag: Sickle-Cell Anemia

Systemic Corticosteroids Tied to Vaso-Occlusive Episodes in Sickle Cell

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Association seen among children and adults with sickle cell disease; association lower for those exposed to hydroxyurea

Male Teens With Sickle Cell Disease Unaware of Related Fertility Issues

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Authors say educational materials and fertility testing options are needed

Risk of Stillbirth Up for Pregnant People With Sickle Cell Trait

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In fully adjusted model, increased risk of stillbirth also seen for those with sickle cell disease, multiple gestations

ASH Issues Guideline on the Use of HSCT for Sickle Cell Disease

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The use of HSCT for sickle cell disease is evolving, and no randomized controlled trials were identified in the evidence review for this guideline

Sickle Cell Disease May Up Risk for Poor COVID-19 Outcomes

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Sickle cell trait also associated with increased risk for COVID-19-related hospitalization and death, but to a lesser extent

Risk Factors ID’d for Severe COVID-19 With Sickle Cell Disease

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Hydroxyurea use does not impact development of serious COVID-19 or need for hospitalization in children or adults

Treatment at Infusion Center Beneficial in Sickle Cell Disease

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Outcomes significantly better for treatment of vaso-occlusive crises at infusion center versus emergency department

Gene Therapy for Sickle Cell Did Not Cause Patient’s Leukemia

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Bluebird Bio says it has not found evidence that its gene therapy caused the sickle cell patient's leukemia

Transplant Beneficial for Kidney Failure in Sickle Cell

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Patients with kidney failure associated with sickle cell disease are less likely to receive a transplant despite similar reduction in mortality

Trial of Gene Therapy for Sickle Cell Disease Halted

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Two patients participating in the study developed cancer years after treatment