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Tag: Sickle-Cell Anemia

FDA Advisers to Weigh New Gene Therapies for Sickle Cell Anemia

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Advisers will consider whether more research is needed into potential unintended consequences of the new therapies

Pneumococcal Infection Reduced in Children With Sickle Cell Since PCV13

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After 2010, all invasive pneumococcal infection serotypes were those not included in 13-valent pneumococcal conjugate vaccine

Sickle Cell Disease Highly Contributes to All-Cause Mortality

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Global sickle cell disease mortality burden was 376,000 in 2021; 81,100 deaths reported in children younger than 5 years

Gene Therapy Not Cost-Effective for Sickle Cell by Conventional Measures

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The inequality aversion parameter would need to be 0.90 for gene therapy to be preferred per distributional cost-effectiveness analysis standards

Study Explores Correlates of Pain Associated With Sickle Cell

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Increased pain frequency seen in association with unemployment, female sex, depression

TKA Complications Increased for Sickle Cell Disease Patients

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Patients with sickle cell disease have longer length of stay, incur greater health care costs, have increased need for step-down health care facilities

Hydroxyurea Underused in Youth With Sickle Cell

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Majority of youth in Michigan and New York with sickle cell anemia did not have filled hydroxyurea prescriptions

Youth With Hematologic, Oncologic Conditions Benefit From Massage

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Benefits seen across all patient conditions for pain, stress, and anxiety

ASA: Stem Cell Transplant Improves Vasculopathy in Sickle Cell Patients

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No patients without evidence of vasculopathy at transplant developed stenoses or aneurysms after hematopoietic stem cell transplantation

U.S. Maternal Mortality, Morbidity Increased in Sickle Cell Disease

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Median of 28.9 percent of the increased risk of deliveries to people with SCD was explained by racial disparities