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Septic Shock Linked to Mortality in Hematologic Malignancies

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Mortality rate increases with increasing sequential organ failure assessment score on admission, respiratory failure, maximum lactate level

2000 to 2019 Saw Decline in Sepsis-Related Death Rates for ≥65s

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Increase in sepsis-related death rates with age, with rate about five times higher for adults aged 85 years or older versus 65 to 74 years

Clinical Benefit of Epic Sepsis Model in Question

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External validation study shows poor performance for proprietary sepsis prediction model in hospitalized patients

Introduction of Sepsis Performance Measure Had Little Impact

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Variable impact found on changes in process measures, with no improvement in clinical outcomes

SB - 2/2 -- Improvements in ICU COVID Treatments May Have Plateaued

Dexmedetomidine No Better Than Propofol for Adults With Sepsis

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For light sedation of mechanically ventilated patients with sepsis, number of days alive without delirium or coma similar between groups

Many at Risk for Severe COVID-19 Have Essential Jobs

Better Hospital Nurse Staffing Tied to Fewer Sepsis Deaths

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Staffing more strongly tied to deaths than adherence to mandated sepsis care bundles

Copy of Black Children Hit Especially Hard by COVID-19 Inflammatory Syndrome

Disparities Seen in Pediatric Sepsis Outcomes in the U.S.

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Black children have higher odds of death; Hispanic and Black children have longer hospital stays, especially Black neonates

Greater nurse staffing and intensivist hours are associated with significantly lower rates of sepsis

Nursing, Intensivist Staffing Tied to Lower Hospital Sepsis Rates

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In contrast, greater physician staffing, hospitalist hours associated with higher sepsis rates
Risk for early-onset neonatal bacterial sepsis increases with maternal overweight and obesity

Maternal Weight Tied to Early-Onset Neonatal Bacterial Sepsis

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Half of this association explained by cesarean section delivery, preeclampsia, preterm delivery