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Late-Onset Meningitis ID’d in 1 Percent of Extreme Preemies

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Performance of lumbar puncture has decreased in late-onset sepsis evaluations; 16 percent of late-onset meningitis cases occurred without late-onset sepsis

7.7 Million Deaths Associated With 33 Bacterial Pathogens in 2019

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Deaths associated with these pathogens comprised 13.6 percent of all global deaths, 56.2 percent of all sepsis-related deaths

AI Algorithm May ID Dysfunctional Immune Profiles in Acute Infection

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Machine learning framework used to deploy quantitative sepsis response signature score, which was estimated using seven- or 12-gene signature

Pediatric Sepsis Survivors May Face New, Progressing Comorbidities

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Nearly one in five have new or worsening medical condition versus nonsepsis critical care survivors

Early Warning System Can Identify Sepsis Patients

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Patients whose alert was confirmed by provider within three hours had reduced in-hospital mortality rate

IV Vitamin C Increases Risk for Death, Organ Failure in Sepsis

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Risk increased with intravenous vitamin C versus placebo for adults with sepsis in the ICU receiving vasopressor therapy

No Fewer Deaths Seen With Restricted IV Fluid for Septic Shock

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Rates of death at 90 days, SAEs did not differ for patients with septic shock receiving restricted versus standard IV fluid therapy in the ICU

Health Care Employee Turnover Recovering

Greater Nurse Staffing Tied to Better Sepsis Outcomes

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An increase in registered nurse hours per patient day was associated with a 3 percent decrease in 60-day mortality

Early-Life Antibiotics Alter Infant Gut Microbiome

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Major shift seen in composition and in antimicrobial resistance gene profile directly after treatment, which normalized over 12 months

Risk for Early-Onset Sepsis Low for Infants With Low-Risk Delivery

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Risk for early-onset sepsis low among infants of all gestational ages born with low-risk delivery characteristics