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Landiolol Does Not Reduce Organ Failure in Septic Shock Patients With Tachycardia

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Mean Sequential Organ Failure Assessment score did not differ for those receiving landiolol and standard care

In-Hospital Mortality Evaluated for SARS-CoV-2-Linked Sepsis

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March 2020 to November 2022 saw decline in crude in-hospital mortality for SARS-CoV-2-linked sepsis from 33.4 to 14.9 percent

Factors ID’d That Increase Risk for Mechanical Ventilation With Sepsis

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However, risk factors change depending on time from diagnosis and comorbidities

Opportunities Exist for Improving Hospital-Based Sepsis Programs With New CDC Guidance

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73 percent of hospitals have a committee that monitors and reviews sepsis care, with prevalence varying by hospital size

Continuous Meropenem No Benefit in Critically Ill Patients With Sepsis

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No improvement seen in composite of all-cause mortality and emergence of pandrug- or extensively drug-resistant bacteria

Hydrocortisone Does Not Reduce 90-Day Mortality in Septic Shock

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Small reduction in mortality seen with use of hydrocortisone with fludrocortisone

Hydrocortisone Plus Fludrocortisone Superior for Septic Shock

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Compared with hydrocortisone alone, combo significantly cuts risk for in-hospital death or hospice discharge

Azithromycin Cuts Maternal Sepsis, Death in Vaginal Delivery

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For women planning vaginal delivery, azithromycin linked to lower risk for maternal sepsis or death

Cardiovascular Hospitalization Increased After Sepsis Hospitalization

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Patients discharged after sepsis hospitalization have increased risk for all-cause mortality, all-cause rehospitalization

Restrictive, Liberal Fluid Strategies Yield Similar Outcomes for Sepsis-Induced Hypotension

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All-cause death before discharge home by day 90 occurred in 14.0 percent of the restrictive fluid group and 14.9 percent in the liberal fluid group