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Recommending pneumococcal vaccination for all 50-year-olds prevents the most disease in underserved minorities and the general population

Pneumococcal Vaccination at Age 50 Prevents the Most Disease

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But cost of giving pneumococcal vaccines to all 50-year-olds exceeds $250,000 per QALY
Delaying or withholding antibiotics for older patients with a urinary tract infection is associated with an increase in bloodstream infection and all-cause mortality

Antibiotic Delay Leads to Increased Risks in Seniors With UTI

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No antibiotics, deferred antibiotics tied to increase in bloodstream infection, all-cause mortality
In older adults

CVD Does Not Modify Depression-Mortality Link in Elderly

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Depression tied to higher death risk in older adults; CVD explains just small fraction of excess mortality
From 2003 to 2016

Improved Outcomes Seen With Liver Grafts From Older Donors

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However, liver graft discard from older donors remained increased from 2003 to 2016
Older patients with severe frailty undergoing transcatheter aortic valve replacement and surgical aortic valve replacement frequently experience subsequent functional decline or lack of improvement

Functional Decline Seen for Many Frail Patients After TAVR, SAVR

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Older patients with severe frailty often have decline or lack of improvement after the procedures
Education is associated with global cognition but not with the rate of cognitive change in older adults

Education Not Tied to Rate of Cognitive Change in Seniors

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Education was not associated with onset, rate of accelerated decline before dementia diagnosis
Older people who develop depression have significantly slower gait speed and shorter step length several years before diagnosis

Slower Gait Speed, Shorter Step Length Tied to Later Depression

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Slowest tertile for gait speed, shortest tertile for step length tied to higher likelihood of depression
Potential antidepressant overprescribing appears to be common among elderly patients and involves mostly newer antidepressants used for nonspecific psychiatric symptoms and subthreshold diagnoses

Antidepressant Overprescribing Appears Common in Elderly

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Overprescribing tied to newer antidepressants, non-face-to-face interactions with prescribers
For older adults undergoing surgery

EEG-Guided Anesthesia Does Not Cut Postop Delirium in Seniors

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Significantly less median cumulative time found with EEG suppression in EEG-guided group vs. usual care
More than 5 percent of seniors visit emergency departments more than six times in one year

Older Adults With Comorbidities Identified as Frequent ED Users

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~5 percent of older adults account for ~20 percent of emergency department visits