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A machine learning process and clinical natural language processing can rapidly diagnose rare genetic diseases

Machine Learning Can Speed Diagnosis of Genetic Diseases in Children

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Automated, retrospective diagnoses concurred well with expert manual interpretation
Cardiovascular risk screening intervals based on risk category-specific progression rates would perform better and improve cost-effectiveness compared with established five-year screening intervals

Risk-Based Screening Improves Cardiovascular Disease Prevention

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Benefits seen for prevention of major cardiovascular events, higher quality-adjusted life years
The U.S. Preventive Services Task Force (USPSTF) recommends screening pregnant women for asymptomatic bacteriuria but not nonpregnant women or men. These recommendations form the basis of a draft recommendation statement published online April 23 by the USPSTF.

USPSTF Urges Asymptomatic Bacteriuria Screen in Pregnancy

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No evidence seen for benefits of screening nonpregnant women or men for asymptomatic bacteriuria
Financial incentives do not increase response rates among patients mailed at-home colorectal cancer screening tests

Financial Incentives Do Not Boost Use of At-Home CRC Screening Tests

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$10 incentives used in the study may have been too small to garner a response
Almost 20 percent of refugee children have elevated blood lead levels

Elevated Blood Lead Levels Prevalent Among Refugee Children

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Correlations seen for EBLL with younger age, male sex, and overseas examination country
An informational film can improve knowledge and reduce decisional conflict for individuals considering participating in lung cancer screening

Informational Film Improves Knowledge on Lung Cancer Screening

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Mean objective and subjective knowledge improved; higher decisional certainty seen with film
The U.S. Preventive Services Task Force has determined that the balance of benefits and harms of screening for elevated blood lead levels in asymptomatic young children and pregnant women cannot be ascertained. This finding forms the basis of an updated final recommendation statement published in the April 16 issue of the Journal of the American Medical Association.

USPSTF: Evidence Lacking for Elevated Lead Level Screening

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Evidence inadequate to determine benefits, harms of screening for asymptomatic children, pregnant women
Adolescent and adult women

Draft Recommendation Promotes Screening Women for Anxiety

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Teen, adult women, including pregnant women, should be assessed for anxiety as part of routine care
Four evidence-based guidance statements on breast cancer screening have been developed by the American College of Physicians and published online April 9 in the Annals of Internal Medicine.

Guidance Statements Issued for Breast Cancer Screening

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Clinicians should discuss mammography with patients aged 40 to 49, discontinue screening for those ≥75
Laboratories vary in the extent to which they adhere to recommendations from the American College of Medical Genetics and Genomics for noninvasive prenatal screening

Adherence to Prenatal Screening Recommendations Varies by Lab

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Laboratories vary in the extent to which they meet ACMG position statement recommendations