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American Society for Radiation Oncology, Oct. 18-21

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The 57th Annual Meeting of the American Society for Radiation Oncology The annual meeting of the American Society for Radiation Oncology (ASTRO) was...
Chemoradiotherapy is associated with survival benefit over chemotherapy alone for elderly patients with limited-stage small-cell lung cancer

CRT May Be Preferred Strategy for Elderly With Lung Cancer

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Increased survival for chemoradiotherapy versus chemotherapy in limited-stage, small-cell lung cancer
Hypofractionated radiation therapy with incorporated boost over a shorter period of time treats early-stage breast cancer as well as longer

ASTRO: Shorter Radiation OK for Early Breast Cancers

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High-dose therapy shows same survival rates as longer course of standard radiation
For patients with incurable head and neck cancer

High-Dose Hypofractionated RT Palliative in Head, Neck Cancer

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Meaningful palliative effect for 63 percent of patients, lasting for median of 4.6 months
Stage IV nonsmall-cell lung cancer patients in the United States often receive more radiation therapy than recommended

Palliative Radiotherapy Often Overused in Stage IV NSCLC

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Not proven to further improve symptoms or quality of life; can have significant side effects
For men with unfavorable-risk prostate cancer

Radiation Tx Impact Varies With Comorbidity in Prostate Cancer

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Reduction in overall, cardiac mortality for RT alone in men with severe or moderate comorbidity
Radiation and chemotherapy can cause structural changes in the healthy brain tissue of patients with glioblastoma brain tumors

Chemoradiation for Glioblastoma Takes Toll on Brain

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Structural changes include reduced gray matter volume and ventricular enlargement
Physicians whose peers were early adopters of brachytherapy for the treatment of women with early-stage breast cancer are more likely to adopt the therapy themselves

Physicians’ Peers Influence Use of New Cancer Tx Modalities

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Exposure to peers who were early adopters of brachytherapy associated with increased use
For women with breast cancer

Hypofractionated Breast Irradiation = Reduced Toxicity

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Two studies show benefits for hypofractionated vs conventionally fractionated whole-breast irradiation
Some women who have surgery for early-stage breast cancer may benefit from additional radiation to nearby lymph nodes

Nodal Radiation Doesn’t Impact Early Breast Cancer Survival

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Researchers find it lowers chances of recurrence, but does not boost overall survival