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Tag: Proton Pump Inhibitors

Acid suppression therapy is associated with increased incidence of kidney stones and chronic kidney disease

ASN: Acid Suppression Therapy Linked to Kidney Stones, CKD

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Two studies show increased risk of kidney stones with PPI, H2 blocker use; CKD with PPI use
Proton pump inhibitors at higher doses are associated with an increased risk of ischemic stroke

AHA: Proton Pump Inhibitors Tied to Ischemic Stroke Risk

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Researchers concerned about high doses of meds like esomeprazole and omeprazole
For patients with cirrhosis with previous spontaneous bacterial peritonitis (SBP)

PPI Use Doesn’t Up Recurrence of Bacterial Peritonitis

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Findings show no increased risk for patients with cirrhosis taking proton pump inhibitors
For patients with gastric adenoma or early gastric cancer

Standard and Double Dose Pantoprazole Equally Effective

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Findings in patients with gastric adenoma or early gastric cancer undergoing endoscopic resection
Advice of regulatory authorities released in 2009 and 2010 regarding safety concerns for concomitant use of clopidogrel and certain proton pump inhibitors (PPIs) was partially followed

Many Still Prescribe Concomitant (Es)omeprazole, Clopidogrel

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Patients on clopidogrel prescribed omeprazole or esomeprazole despite safety warnings