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Metformin, Ivermectin, Fluvoxamine Do Not Prevent Severe COVID-19

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No difference in the primary end point seen with any of the three medications versus placebo among adults with overweight or obesity

Ticagrelor DAPT Linked to Lower Risk for Vein Graft Failure in CABG

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But addition of ticagrelor linked to increased risk for BARC type 2, 3, or 5 bleeding events versus aspirin

Dupilumab Studied in Patients Hospitalized for COVID-19

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No difference seen between dupilumab and placebo groups in adverse events or primary outcome of ventilator-free survival at 28 days

Mepolizumab Cuts Exacerbations in Children With Severe Asthma

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Trial enrolled children from disadvantaged urban neighborhoods who have exacerbation-prone eosinophilic asthma

How Will New Federal Legislation Cut Drug Costs?

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Under the law, Medicare will now be allowed to negotiate the cost of some drugs; vaccines will be free for Part D recipients

Direct-to-Consumer Advertising Has Positive Impact on Rx Demand

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Large and positive association seen with medication-related demand intentions, with no negative impact on lifestyle-related intentions

Survival Benefit Seen With Triple Therapy for Severe COVID-19

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Compared with dual therapy, significant survival benefit seen with dexamethasone, remdesivir, and baricitinib but no change in length of stay

Polypharmacy Prevalent Among Older Adults With Blood Cancers

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Taking eight or more medications strongly associated with frailty; odds of being prefrail, frail increased with each additional med

Use of Medication Therapy for Opioid Use Disorder Increased 2010 to 2019

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However, 86.6 percent of people with opioid use disorder are not receiving medication treatment

Few Insured Individuals Receive Timely DAA Treatment for Hep C

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Individuals with Medicare and Medicaid have lower odds of treatment initiation than those with private insurance