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SARS-CoV-2 mAbs Continued to Be Used After FDA Deauthorization

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More than 158,000 doses of bamlanivimab-etesevimab and casirivimab-imdevimab were used after deauthorization on Jan. 24, 2022

Polypill Cuts Cardiovascular Event Risk in Seniors With Recent MI

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Polypill comprising aspirin, ramipril, atorvastatin effective for secondary prevention of cardiovascular disease in older adults

Dapagliflozin Cuts CV Risk in Heart Failure With Preserved LVEF

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Risk reduced for primary outcome of worsening heart failure or cardiovascular death

Acetazolamide Helps Treat Volume Overload in Heart Failure

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Rate of successful decongestion higher with addition of acetazolamide to loop diuretic in patients with acute decompensated heart failure

Tecovirimat Well Tolerated for Treatment of Monkeypox

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By day 21, 23 of 25 patients had resolution of lesions and pain; none of the patients discontinued treatment

Industry Payments to Prescribers May Influence Choice of Eye Drops

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Positive association seen between amount of transfers of value and frequency of prescribing branded prostaglandin analog eye drops

Rates of Severe COVID-19 Lower With Nirmatrelvir in ≥65s

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Rate of hospitalization due to COVID-19 and death reduced for treated versus untreated patients among those aged 65 years and older

Olokizumab Tops Placebo for RA Patients Receiving Methotrexate

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Olokizumab superior to placebo and noninferior to adalimumab in producing ACR20 response at 12 weeks

ACOG Develops Consensus on Medical Menstrual Suppression

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Guidance emphasizes role of hormonal therapy and should be accompanied by counseling, including discussions of effectiveness of therapy

Out-of-Pocket Costs for Naloxone Up for Uninsured Patients

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For 2018 compared with 2014, mean out-of-pocket cost of naloxone increased by 506 percent among uninsured patients