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Cefepime/Enmetazobactam Noninferior for Complicated UTI

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Cefepime/enmetazobactam is noninferior and superior to piperacillin/tazobactam for clinical cure and microbial eradication

Lenabasum Studied for Refractory Cutaneous Dermatomyositis

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Results of phase 2 study suggest clinical benefit and favorable safety profile, warranting further study of lenabasum for DM

Order of Radiation Sickness Drug Unrelated to Recent Events in Ukraine

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U.S. health officials say it is only coincidental that the order of Nplate comes just as Russia is making nuclear threats

Telmisartan Does Not Improve Six-Minute Walk Distance in PAD

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Six-minute walk distance not improved with telmisartan versus placebo in patients with lower-extremity peripheral arterial disease

Treatments Compared for Pediatric-Onset Multiple Sclerosis

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More pediatric patients free of new or newly enlarging T2 lesions at week 96 with dimethyl fumarate versus interferon beta-1a

Pirfenidone Promising for RA-Linked Interstitial Lung Disease

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Phase 2 trial terminated early, underpowered to meet primary end point, but limited results suggest pirfenidone may slow progression of RA-ILD

Apremilast May Offer Cardiometabolic Benefit in Psoriasis Patients

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5 to 6 percent decrease seen in subcutaneous and visceral adiposity at week 16 of treatment, which was maintained at 52 weeks

Rituximab Studied as Add-On Therapy for New-Onset Myasthenia Gravis

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Probability of minimal MG manifestations greater, need for rescue medications reduced with rituximab versus placebo

Certain Meds Not Cost-Effective for First-Line Therapy of T2DM

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Compared with metformin, SGLT2 inhibitors, GLP-1 receptor agonists cost more for treatment in drug-naive patients with type 2 diabetes

Research & Development Investments Do Not Explain Drug Price Variation

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No association seen between estimated R&D investments and treatment costs based on list prices at launch or net prices after one year