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Occurrence of Cardiovascular Events, Death Compared Between Thiazides

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Occurrence of major cardiovascular events, non-cancer-related deaths no lower with chlorthalidone versus hydrochlorothiazide

Progression-Free Survival Increased With Zanubrutinib in Leukemia

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Longer progression-free survival seen with zanubrutinib versus ibrutinib for patients with relapsed or refractory chronic or small lymphocytic leukemia

Congressional Report Slams FDA, Drugmaker Over Approval of Alzheimer Drug Aduhelm

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Controversy over Aduhelm stretches back to its June 2021 approval by the U.S. Food and Drug Administration

Molnupiravir Does Not Reduce COVID-19-Related Hospitalization, Death

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No reduction in COVID-19-associated hospitalizations or deaths seen among high-risk, vaccinated adults

5α-Reductase Inhibitors Linked to Depression, but Not Dementia

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Magnitude of association for finasteride and dutasteride with dementia decreased over time and became nonsignificant

Weekly Dupilumab Beneficial in Eosinophilic Esophagitis

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More patients receiving dupilumab have histologic remission, improvement in Dysphagia Symptom Questionnaire scores

FDA Approves Gene Therapy for Tough-to-Treat Bladder Cancer

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About 57,000 men and 18,000 women are diagnosed with bladder cancer annually

Metformin Use Linked to Lower Risk for Joint Replacement in T2DM

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Reduced risk seen for total knee replacement and total hip replacement with metformin use

ASH: Glofitamab Aids Relapsed, Refractory Diffuse Large B-Cell Lymphoma

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39 percent of patients had a complete response, with median time to complete response of 42 days

Sublingual Buprenorphine/Naloxone Tied to More Adverse Dental Outcomes

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More adverse dental outcomes seen with sublingual buprenorphine/naloxone compared with use of transdermal buprenorphine or oral naltrexone