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Dual-Targeted Therapies Plus Chemo Improve Objective Response Rate in BRAF V600E Metastatic CRC

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Significant and clinically relevant improvement seen in objective response rate with encorafenib + cetuximab plus mFOLFOX6

FDA Approval Expands Earlier Use of Enhertu for Metastatic Breast Cancer

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Approval is targeted for patients with HER2-low or HER2-ultralow metastatic breast cancer with disease progression after endocrine therapy

FDA Approves Datroway for HR-Positive, HER2-Negative Breast Cancer

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Approval is for those who have had prior therapy for unresectable or metastatic disease

Distribution of Opioid Meds Lower in Majority Non-White Communities

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In a recent study, majority non-White communities had at least 40 percent lower mean adjusted per-capita distribution than majority White communities

Propranolol May Reduce Overall Stroke Risk in Women With Migraine

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Protective effect more pronounced for ischemic stroke and in women with migraine without aura

Diabetes Remission Increased With Dapagliflozin Plus Calorie Restriction

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Dapagliflozin plus calorie restriction beneficial for patients with overweight or obesity and type 2 diabetes

Recent Decades Saw Rise in Sedative, Hypnotic, Anxiolytic Use Disorders

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Findings seen among adolescent and young adult Medicaid enrollees

Guidance Developed for Diagnosis, Management of Eosinophilic Esophagitis

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Suggested treatments for eosinophilic esophagitis include PPIs, topical steroids, empiric food elimination diet, biologics, endoscopic dilation

Considerable Uncertainty Exists Regarding Effects of Puberty Blockers

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Two systematic reviews revealed very low-certainty evidence on outcomes for people with gender dysphoria

Lower Dexamethasone Dose Does Not Impair Survival in Multiple Myeloma

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Progression-free and overall survival do not differ for patients receiving full-dose, lowered-dose dexamethasone throughout induction