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FDA Advisers Back Full Approval of Paxlovid

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Panel of FDA advisers says the medication remains safe and effective for high-risk patients

Clozapine, ECT, Lithium May Prevent Suicide in Male Teens With Severe Mental Illness

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Regional clozapine, ECT, and lithium treatment frequency related to lower adolescent excess suicide mortality for 15- to 19-year-olds

Lebrikizumab Effective for Adults, Teens With Atopic Dermatitis

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In two phase 3 trials, lebrikizumab effective for primary outcome of IGA score of 0 or 1 and for achieving EASI-75

PEPFAR Has Scaled Up HIV ART to About 20 Million Persons Since 2004

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Variability seen in viral load coverage and in viral load suppression among distinct subpopulations

ACC: Coordinated Intervention Increases Rx for Evidence-Based T2DM Therapies

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Multifaceted intervention of assessment, education, and feedback increases likelihood of triple prescription fourfold over usual care

FDA Approves First Treatment for Rett Syndrome

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Approval of Daybue applies to adults and children aged 2 years and older

Hydrochlorothiazide Does Not Affect Recurrence of Kidney Stones

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For patients with recurrent kidney stones, no difference seen in recurrence with hydrochlorothiazide 12.5, 25, 50 mg versus placebo

Nirogacestat Beneficial for Progressing Desmoid Tumors

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Significant progression-free survival benefit seen over placebo; more patients receiving nirogacestat have objective response

Viral, Symptom Rebound Common After COVID-19 Infection

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Incidence of symptom rebound was higher in the nirmatrelvir plus ritonavir treatment group

Preterm Birth Drug Pulled From Market Over Lack of Effectiveness

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FDA has been proposing to remove Makena from the market since October 2020, a decision appealed by the drug maker