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Fixed-Duration Ibrutinib Plus Venetoclax Beneficial for Leukemia

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Overall response rates >95 percent, regardless of high-risk features; 36-month PFS 88 and 92 percent for those with, without high-risk features

Outpatient Metformin Treatment Reduces Incidence of Long COVID

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Beneficial effect of metformin consistent across subgroups

Valbenazine Yields Improvement in Chorea in Huntington Disease

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Improvement seen in Unified Huntington's Disease Rating Scale Total Maximal Chorea with valbenazine versus placebo

ASCO: Adding Atezolizumab to Cabozantinib No Benefit in Advanced Renal Cancer

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No improvement seen in disease progression or death, and increase seen in serious adverse events with atezolizumab + cabozantinib

ASCO: Cilta-Cel Beneficial for Lenalidomide-Refractory Multiple Myeloma

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Single cilta-cel infusion results in lower risk of disease progression or death compared with standard care

ASCO: Drug Combo Ups Progression-Free Survival for Metastatic Prostate Cancer

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Improvement in radiographic progression-free survival seen for talazoparib plus enzalutamide as first-line treatment

Semaglutide Better Than Liraglutide for Post-Bariatric Surgery Weight Recurrence

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Findings seen for weekly semaglutide versus daily liraglutide regardless of procedure type

Semaglutide Reduces BMI Category for Adolescents With Obesity

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Improvement of one or more BMI category seen for majority of participants receiving semaglutide

Spironolactone Found to Improve Acne in Adult Women

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Mean quality-of-life symptoms favor spironolactone at 12 and 24 weeks; more participants report acne improvement with spironolactone

Nirmatrelvir-Ritonavir Effective for Outpatient Treatment of COVID-19

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Reduces 30-day risk for hospitalization and death, while only death was reduced in association with molnupiravir