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Most of the Effect of Paroxetine for Treating Hot Flashes May Be Placebo Effect

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Authors say mean treatment effect for hot flash frequency may only be 21 percent

Concizumab May Be Effective Prophylaxis for Hemophilia A or B With Inhibitors

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Overall median annualized bleeding rate was 0 with concizumab

Rates of Tx Retention for Rifaximin Low Despite Benefits for Hepatic Encephalopathy

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Lower treatment retention rates seen with 30-day, out-of-pocket costs ≥$150

Heart, Diabetes, Cancer Drugs on List for Medicare Price Negotiations, White House Says

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Enrollees in the Medicare prescription drug program paid a total of $3.4 billion in out-of-pocket costs in 2022 for the 10 initial drugs chosen for price negotiations

Most Immunosuppressive Drugs Not Linked to Risk for Cancer

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No associations seen for TNF inhibitor, antimetabolite, calcineurin inhibitor, or alkylating agent classes with cancer

USPSTF Reaffirms Recommendation of PrEP for Those at Increased HIV Risk

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Considerable net benefit seen for use of effective antiretroviral therapy for reducing risk for HIV acquisition

Tardive Dyskinesia Has Considerable Impact on Multiple Domains

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Considerable impact scores reported in physical, psychological, social domains; professional lives also affected

Dupilumab Treatment Beneficial for Sleep in Atopic Dermatitis

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12 weeks of treatment also yields benefits in peak pruritus, change in SCORing Atopic Dermatitis

Budesonide Yields Durable Reduction in eGFR for IgA Nephropathy

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Clinically relevant reduction in eGFR seen over two years with targeted release formulation of budesonide

Eligibility Limited for Anti-β Amyloid mAbs in Seniors With MCI

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Few older adults with MCI or mild dementia were eligible for lecanemab, aducanumab after applying clinical trial criteria