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Real-World Study Shows Effectiveness of Ixekizumab for Psoriasis

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Significant clinical improvements seen with and without induction therapy, with faster initial response with induction

Weight Loss After Antiobesity Medication Initiation Lowers Joint Revision Risk

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Higher weight loss after initiating antiobesity meds linked to lower risk for revision of hip and knee replacement

Obinutuzumab Efficacious for Renal Response in Lupus Nephritis

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More patients receiving obinutuzumab plus standard therapy versus standard therapy alone had a complete renal response at week 76

One in Six Patients in Phase 2 Cancer Trials Receive Drug When Eventually Approved

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Proportion increases when considering off-label use but drops when considering drugs with substantial clinical benefit

Acalabrutinib-Venetoclax Prolongs Survival in Previously Untreated Leukemia

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Progression-free survival significantly lower with fixed-duration acalabrutinib-venetoclax with or without obinutuzumab

Olpasiran Leads to Significant Reduction in Oxidized Phospholipids

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Olpasiran leads to significant and sustained reduction in OxPL on apolipoprotein B

Certain Glucose-Lowering Meds Associated With Lower Risk for COPD Exacerbations

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Lower risk for COPD exacerbations seen with SGLT-2 inhibitors and GLP-1 receptor agonists, but not with DPP-4 inhibitors

Anifrolumab Tied to Less Organ Damage for Patients With Lupus

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Lower likelihood seen for experiencing increase in Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index

Talazoparib + Enzalutamide Tied to Improved Overall Survival in Metastatic Prostate Cancer

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Talazoparib + enzalutamide linked to improved survival for patients with mCRPC unselected for HRR gene alterations

De-Escalating DAPT to Ticagrelor Monotherapy Cuts Bleeding Risk in Acute Coronary Syndrome

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Lower risk for bleeding without increase in ischemic events seen for patients with acute coronary syndrome