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Industry Payments to Doctors Tied to Nonrecommended, Low-Value Drug Use

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Payment from industry associated with increased use of denosumab, GCSF, and nab-paclitaxel, lower use of branded drugs

In Utero Corticosteroid Exposure Not Detrimental to Offspring Neurodevelopment

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However, for β2-adrenergic agonists, association seen between mid-to-late pregnancy exposure and delayed personal-social skills

Patisiran Can Preserve Functional Capacity in ATTR Amyloidosis

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Decline in six-minute walk distance lower in patisiran versus placebo group at month 12

Nemolizumab Improves Symptoms in Prurigo Nodularis

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Treatment efficacy seen in primary end points of itch response and Investigator's Global Assessment response

Tapinarof Cream Safe, Effective for Plaque Psoriasis in Intertriginous Areas

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12-week benefits include high rates of skin clearance, meaningful itch relief

ESMO: Pembrolizumab + Chemo, Trastuzumab Beneficial in Gastroesophageal Cancer

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Improvement seen in progression-free survival with add-on pembrolizumab in gastroesophageal junction adenocarcinoma

Ketamine No Better Than Placebo for Depression

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Intravenous ketamine delivered during surgical anesthesia has no greater effect than placebo in reducing severity of depression

Sotorasib + Panitumumab Beneficial for Chemorefractory Metastatic CRC

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Reduced hazard ratio seen for disease progression or death with sotorasib-panitumumab versus standard care

Survival Improved With Everolimus in High-Risk Clear Cell Renal Cancer

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Findings seen in clear cell renal cell carcinoma patients at very high disease risk after nephrectomy from EVEREST trial

Teplizumab Beneficial for Preserving Beta-Cell Function in Pediatric T1D

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Benefit seen for preservation of β-cell function in children and adolescents with newly diagnosed type 1 diabetes