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Concomitant use of metformin and histamine H2-receptor antagonists or proton pump inhibitors has the potential to induce vitamin B12 depletion and neuropathy

Concomitant Metformin, GERD Meds Up Vitamin B12 Depletion

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Concomitant use of these medications may result in B12 deficiency-induced neuropathy
Direct-to-consumer advertising of asthma medications is associated with increased emergency department utilization among commercially insured patients

Direct-to-Consumer Advertising of Asthma Meds Ups ER Use

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Advertising linked to increase in pharmacy sales; emergency room visits for commercially insured
Prednisolone and pentoxifylline are associated with limited and no benefits

Prednisolone, Pentoxifylline Little Use in Alcoholic Hepatitis

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Nonsignificant drop in 28-day mortality with prednisolone; no improvement with pentoxifylline
Despite evidence that has suggested metformin might have potential in cancer

AACR: Metformin Benefit Lacking in Pancreatic Ductal CA

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Survival not significantly different for pancreatic ductal adenocarcinoma patients
Opioids that have features that make them hard to abuse may be linked to a drop in both the number of prescriptions and overdoses of these drugs

Changing Opioid Rx Formulations May Help Curb Abuse

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As opioid market changed, number of prescriptions, overdoses dropped, but heroin overdoses went up
At least five different strategies may help children swallow pills and capsules more easily

Strategies Successful for Helping Children Swallow Meds

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Five strategies identified that help get the medicine down
Both residents and attending physicians are only partly compliant with national opioid prescribing and monitoring guidelines

Attending Physicians, Residents Similar in Opioid Rx Monitoring

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Residents provide more early refills; also see more patients at higher misuse risk
Immune checkpoint inhibitors show promise in treating advanced melanoma

AACR: Immune Checkpoint Inhibitors Promising in Melanoma

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Pembrolizumab, ipilimumab, and other medications harness immune cells to target cancers
Hydroxychloroquine appears to be associated with lower risk of hyperlipidemia in patients with early rheumatoid arthritis

Hydroxychloroquine May Reduce Hyperlipidemia Risk in Early RA

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Reduced risk of hyperlipidemia with hydroxychloroquine versus other DMARDs
For patients with Behçet's syndrome

Apremilast Effective for Oral Ulcers in Behçet’s Syndrome

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Reduction in number of oral ulcers per patient; greater decline in pain from ulcers with apremilast