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The benefit of sublingual immunotherapy over placebo for seasonal grass pollen allergies is small

Sublingual Immunotherapy Offers Little Benefit for Grass Allergy

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For serious seasonal allergies, shots may be more effective, researcher says
A new naloxone sustained release capsule appears to be safe and efficacious for opioid-induced constipation

New Naloxone Capsule Safe for Opioid-Induced Constipation

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Sustained release formula efficacious, with no indication of opioid withdrawal or increase in pain
Physicians who are ill-informed about opioids may be unintentionally contributing to their misuse

Many Primary Care Physicians Misinformed About Opioids

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Nearly half questioned were misinformed about potential for abuse
For patients with chronic pain

Methadone Linked to Initial QTc Prolongation in Chronic Pain

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Nonsignificant increase in QTc in first month after initiating methadone, which does not persist
Prenatal exposure to H2 blockers or proton pump inhibitors is associated with a small but significantly increased risk of asthma in offspring

Prenatal Exposure to H2 Blockers, PPIs Ups Asthma Risk

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Small but significantly increased risk of asthma in offspring; higher risk with greater exposure
Pharmacist-managed warfarin therapy is superior to a usual medical care model for management of warfarin therapy

Pharmacist-Managed Warfarin Therapy Beats Usual Care

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Percentage of time in therapeutic range, major bleeding events, hospitalization all in favor of PMWT
A new review of data involving over 20

Viagra, Other ED Meds Don’t Raise Melanoma Risk

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Slightly higher odds for men on ED drugs, but lifestyles are probable culprit
Researchers report that a drug for rheumatoid arthritis may be a promising treatment for vitiligo. The findings were published online June 24 in JAMA Dermatology.

Drug for Rheumatoid Arthritis May Also Help Ease Vitiligo

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Case study showed tofacitinib cleared up skin pigmentation loss in woman after just two months
Optimal management of subtherapeutic international normalized ratios is unclear

Variability Identified in Bridging Practices Among Pharmacists

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In some scenarios, significant differences with varying levels of experience, residency training
Forgoing bridging anticoagulation therapy is noninferior to bridging with low-molecular-weight heparin in patients with atrial fibrillation undergoing an elective operation or invasive procedure. The finding was published online June 22 in the New England Journal of Medicine to coincide with the International Society on Thrombosis and Haemostasis 2015 Congress

Forgoing Bridging Anticoagulation Noninferior in A-Fib

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Findings in patients with atrial fibrillation undergoing elective operation, invasive procedure