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An experimental drug

New Drug Effectively Lowers Levels of Triglycerides

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But it's not yet ready for standard care
The selective Hedgehog antagonist PF-04449913 seems safe and is tolerated in adults with myeloid malignancies

New Rx for Myeloid Malignancies Moves to Phase II Clinical Trials

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Phase I trial involving 47 patients identified maximum tolerated dose of 400 mg once daily
For canagliflozin-treated patients with type 2 diabetes

Low Incidence of Diabetic Ketoacidosis With Canagliflozin

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Canagliflozin-treated patients with type 2 diabetes have low incidence of serious adverse DKA events
For Japanese patients who have undergone percutaneous coronary intervention

Atorvastatin/Ezetimibe Beats Atorvastatin After PCI

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Combination therapy linked to greater coronary plaque regression in Japanese patients
About 10 percent of cases where a drug does serious harm are not reported to the U.S. Food and Drug Administration within the required 15-day period

Delays Noted in the Reporting of Serious Patient Harms to FDA

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Analysis found roughly 10 percent of cases were filed after 15-day deadline passed
Researchers say they've made preliminary progress toward developing a drug that one day may treat people infected with the Marburg virus

Progress Reported in Treatment of Marburg Virus

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Researchers found infected monkeys were less likely to die with treatment
Soaring costs for cancer drugs are detrimental to patient care in the United States

Oncologists Offer Strategies for Reducing Cost of Cancer Drugs

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Suggest letting Medicare negotiate prices; back grassroots movement calling for change
There's more evidence that two classes of generic drugs (aromatase inhibitors and bisphosphonates) reduce the risk of death in postmenopausal women with early breast cancer

Generic Meds Boost Survival in Some Early Breast Cancers

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Researchers found benefit from aromatase inhibitors and bisphosphonates
Bevacizumab is safe and stable when stored at 4 degrees Celsius

Bevacizumab Safe, Stable for Multiple Dosing From Single Vial

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No evidence of infection, inflammation when bevacizumab is stored at 4° Celsius for a week
Pharmacological thromboprophylaxis does not reduce the risk of venous thromboembolism in patients with cirrhosis

Pharmacological Prophylaxis Doesn’t Cut VTE in Cirrhosis

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Low rate of VTE in hospitalized patients with cirrhosis; unaffected by pharmacological prophylaxis