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Doxycycline May Cut Bleeding With Ventricular Assist Device

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ADAMTS-13 is clinical target to cut pathologic vWF degradation with LVAD support
Trends in opioid use and treatment of opioid use disorder are described in two studies published online Oct. 13 in the Journal of the American Medical Association.

Prescription Opioid Use Disorders Up From 2003 to 2013

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Second study shows no increase in treatment for individuals with opioid use disorders
Primary care providers are the sole physician managers for more than one-third of children receiving mental health care

One-Third of Children See PCPs for Mental Health Conditions

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More than 40 percent of children with ADHD see primary care provider only
Multiple sclerosis patients taking daclizumab high yield process

Study of Daclizumab Yields Mixed Results in Multiple Sclerosis

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Relapse rates with daclizumab were lower than with a standard therapy, but side effects were greater
The incidence of cytomegalovirus infection/disease is reduced in de novo kidney transplant recipients receiving reduced dose tacrolimus and everolimus

Reduced-Dose Tacrolimus, Everolimus Cuts CMV Infection

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Findings in de novo kidney recipients receiving no pharmacologic CMV prophylaxis
In adults with episodic migraine

Simvastatin, Vitamin D3 Combo Helps Prevent Migraines

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Treatment effective for preventing headache in adults with episodic migraine
Patients taking β-blockers may face heightened risks of cardiovascular complications during non-cardiac surgeries

β-Blockers May Up Risk of Surgical Complications for Some

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Heightened risks of cardiovascular complications seen during non-cardiac surgeries
For patients with type 2 diabetes mellitus treated with metformin

Add-On Sitagliptin Cuts Risk of Insulin Initiation in T2DM

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Risk of insulin initiation lower for sitagliptin versus sulphonylurea as add-on to metformin
A new treatment for melanoma that combines two cancer drugs has been approved by the U.S. Food and Drug Administration. The therapy for advanced melanoma includes the drugs Yervoy (ipilimumab) and Opdivo (nivolumab)

FDA Approves New Combo Therapy for Melanoma

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Yervoy and Opdivo previously approved individually to treat melanoma
Two experimental drugs

Two Experimental Drugs Promising for Psoriasis Rx

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Targeted therapies produce significant results, researchers say