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Tag: Prescription Drugs

Conventional non-pharmacologic and pharmacologic options for the management of opioid-induced constipation in pregnancy are often ineffective or cause potentially troublesome adverse effects

Opioid-Related Constipation Tx Suboptimal in Pregnancy

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PAMORA strategy appears to safe with superior effectiveness
Omalizumab appears to be highly effective for the management of severe allergic asthma

Omalizumab Highly Effective for Severe Allergic Asthma

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Review of "real-life" studies shows improvements across objective and subjective burden of illness
For patients with major depressive disorder

CYP2C19 Polymorphisms Impacts Citalopram Metabolism

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CYP2C19*2 polymorphism seems to contribute to interindividual variability in CIT metabolism
More frequent monitoring may be required when patients are taking both acenocoumarol and levofloxacin due to the possibility of an adverse interaction

Interaction Described Between Acenocoumarol, Levofloxacin

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Probable interaction described in five patients, all of whom had atrial fibrillation
Teens who use abuse prescription drugs such as opioids are more likely to have sex or to participate in risky sexual behaviors

Abuse of Prescription Drugs Ups Sexual Risks for Teens

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Those taking these drugs with no prescription more likely to have multiple partners, forgo condom use
For patients with non-small-cell lung cancer

Toxic Skin Effects Common With EGFR-TKI Use in NSCLC

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Afatinib therapy linked to earlier paronychia onset; more dermatological visits for skin toxic effects
Postmenopausal women with hormone receptor-positive ductal carcinoma in situ have similar recurrence rates of disease whether they take tamoxifen or the aromatase inhibitor anastrozole after surgery

SABCS: Tamoxifen, Anastrozole Both Prevent Recurrence in DCIS

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However, side effects differ for the two medications
Patients with rheumatoid arthritis have increased herpes zoster risk with older age and higher prednisone dose

Herpes Zoster Risk in RA Up With Older Age, Prednisone Dose

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HZ risk comparable after initiation of TNFi, non-TNFi, and conventional synthetic DMARDs
Pharmaceutical industry-sponsored studies are more likely to report favorable estimates in cost-effectiveness analysis of drugs used in breast cancer treatment

Industry-Led Oncology Trials May Inflate Cost-Effectiveness

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Breast cancer cost-effectiveness analyses show favorable estimates with industry funding
Nitrates don't improve quality of life or everyday activity levels as intended in patients with heart failure

Nitrates in Heart Failure May Harm More Than Help

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Nitrates reduce activity, quality of life, researchers find