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Clinicians prescribing methylphenidate for treatment of attention-deficit/hyperactivity disorder in children and teens must weigh the benefits and adverse effects in the context of low-quality evidence

Low-Quality Evidence for Methylphenidate in ADHD

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Review highlights need for long-term, large, better-quality randomized trials
Between 2009 and 2015

Dermatologic Drug Prices Up Substantially From 2009

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Findings for brand-name meds; generics also increased substantially from 2011 to 2014
Physicians should prescribe generic medications whenever possible

ACP: Physicians Should Prescribe Generic Meds If Possible

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Brand name medications not superior to molecularly identical generic medications
The Bowel Function Index is a simple assessment tool for opioid-induced constipation

Bowel Function Index Valid for Opioid-Induced Constipation

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Three-item index is psychometrically valid, responsive to symptom severity
CYP2C19 polymorphism impacts response to proton pump inhibitor treatment in gastroesophageal reflux disease

CYP2C19 Polymorphism Impacts Response to PPI Tx in GERD

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Meta-analysis shows lower efficacy rates to proton pump inhibitors for rapid metabolizer genotype
California and Oregon will soon implement groundbreaking laws that enable women to get contraceptives from pharmacists without a doctor's prescription.

Two States to Allow Pharmacists to Prescribe Birth Control

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Contraceptives prescribed by pharmacists will be covered by insurance
Terlipressin therapy can induce hyponatremia

Terlipressin Therapy Can Induce Hyponatremia

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Case report describes 41-year-old man with variceal rebleeding treated with terlipressin
Uptake of the women's libido-boosting pill flibanserin (Addyi) has been slow since its approval

Slow Uptake of Women’s Libido-Boosting Pill

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In contrast to sildenafil, only 227 prescriptions written for flibanserin in first few weeks
Infants being breastfed by HIV-positive mothers can effectively be protected from the infection in the six- to 12-month period after birth by receiving up to 12 months of liquid formula HIV drugs

HIV Prophylaxis to 12 Months Protects Breastfeeding Infants

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Both lopinavir-ritonavir, lamivudine linked to very low rates of HIV-1 postnatal transmission
Animal studies have uncovered a compound that might reduce the adverse effects of levodopa. The research was published in the Nov. 18 issue of Neuron.

New Compound May Help Reduce Side Effects From Levodopa

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Studies in mice, monkeys point to a compound that might lessen levodopa's debilitating effects