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Exposure to opioids is associated with increased likelihood of low testosterone levels

Opioid Exposure Tied to Higher Odds of Low Testosterone Levels

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Increased odds of low testosterone with exposure; increased odds with increasing age, comorbidities
Metformin reduces soluble fms-like tyrosine kinase 1 and soluble endoglin secretion from primary human tissues

Metformin Looks Promising in the Treatment of Preeclampsia

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Reduces sFlt-1 and sENG secretion from primary human tissues; reduces endothelial dysfunction
For children and young adults who have a parent with major mood and psychotic disorders

Family Hx Ups Risk of Psychotic Symptoms in Kids on Stimulants

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Findings presented for children of parents with major mood and psychotic disorders
For men with metastatic prostate cancer

More Adverse Effects for Medical Castration in Prostate Cancer

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Higher risks of several clinically relevant adverse effects compared with surgical castration
For patients with cancer

Finances Affect Patient Decisions About Cancer Clinical Trials

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Greater financial concern linked to lower self-efficacy and preparation for decision making
Patients with a nonfatal opioid overdose are almost always prescribed opioids after overdose

After Nonfatal Overdose, Most Patients Prescribed More Opioids

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Cumulative incidence of repeated overdose 17 percent for those receiving high doses after overdose
Preoperative anticoagulation can safely be given to certain patients before major cancer surgery

Pre-Op VTE Prophylaxis Safe in Major Cancer Surgery

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Results led Sloan Kettering to change preoperative practices
For patients with suspected onychomycosis

Empirical Treatment More Cost-Effective for Onychomycosis

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For onychomycosis, empirical tx with terbinafine more cost-effective than confirmatory testing
For patients with psoriasis

Anti-TNF Treatment Ups ANA Positivity in Psoriasis

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Increased antinuclear antibody positivity, but no change in PASI-75 response rates
For patients with angina pectoris

Ivabradine Improves Angina-Related Quality of Life

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No change in primary outcome of change in physical limitation score at 12 months