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From 2008 to 2014 there was an increase in drug shortages within the scope of emergency medicine practice

Drug Shortages Affecting Emergency Med Up 2008 to 2014

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Increases seen in drugs used as direct lifesaving intervention or for high acuity conditions
A single intravenous cyclosporine A bolus just before primary percutaneous coronary intervention has no beneficial effects on ST-segment resolution in reperfused myocardial infarction

No Beneficial Effects Seen for Cyclosporine A in Reperfused MI

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Does not improve ST-segment resolution, hs-cTnT, clinical outcomes, or LV remodeling
For children with infantile hemangiomas

Serious Propranolol ADRs Rare in Infantile Hemangioma

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Most commonly reported adverse drug reactions were respiratory disorders
Patients treated with adjuvant endocrine therapy for primary breast cancer have considerable symptom burden

Considerable Symptom Burden With Adjuvant Endocrine Tx

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Findings among women treated with aromatase inhibitors or tamoxifen for primary breast cancer
Ivacaftor is a potential new treatment to offer children aged 2 years and older with cystic fibrosis and a CFTR gating mutation

Ivacaftor Appears Efficacious, Safe for Younger CF Patients

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Researchers find treatment works and is well tolerated in 2- to 5-year-olds with cystic fibrosis
Curcumin can attenuate acetaminophen-induced mitochondrial alterations in the livers of mice

Curcumin Cuts Acetaminophen-Induced Hepatotoxicity in Mice

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Protective effect of curcumin linked to attenuation of mitochondrial dysfunction
Intravenous thrombolysis treatment might benefit stroke patients who needed help with daily living before their stroke

IV Thrombolysis Aids Patients Dependent Before Their Stroke

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Study finds favorable results among older adults who already had health problems
Eluxadoline (Viberzi) for irritable bowel syndrome with diarrhea seems to reduce symptoms for some patients for at least six months

Eluxadoline Eases Pain and Diarrhea for Some With IBS

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Medication was approved recently by the U.S. Food and Drug Administration
Medication errors associated with antituberculosis therapy occur frequently in an inpatient setting

TB Therapy-Linked Medication Errors Occur Frequently

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More than half of study patients had at least one medication error linked to antituberculosis therapy
Youths treated with antipsychotics have increased cumulative risk and exposure-adjusted incidence of type 2 diabetes mellitus

Antipsychotic-Exposed Youths Have Increased T2DM Risk

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Increased cumulative risk and incidence rate ratio compared with healthy controls, psychiatric controls